| Entry |
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| Name |
Epinephrine bitartrate (JAN/USP);
Asmatane mist (TN);
Medihaler-epi (TN)
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| Formula |
C9H13NO3. C4H6O6
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| Exact mass |
333.106
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| Mol weight |
333.2913
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| Structure |
     |
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| Activity |
Adrenergic [ophthalmic] [DS: H00079]
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| Remark |
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| Comment |
Indication: Bronchial asthma
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
| beta-Adrenergic receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AD Other agents for local oral treatment
A01AD01 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
B BLOOD AND BLOOD FORMING ORGANS
B02 ANTIHEMORRHAGICS
B02B VITAMIN K AND OTHER HEMOSTATICS
B02BC Local hemostatics
B02BC09 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA24 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA14 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AA Alpha- and beta-adrenoreceptor agonists
R03AA01 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA01 Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
USP drug classification [BR:br08302]
Respiratory Tract Agents
Bronchodilators, Sympathomimetic
Epinephrine
D02149 Epinephrine bitartrate (JAN/USP)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
Epinephrine [ATC:A01AD01 B02BC09 C01CA24 R01AA14 R03AA01 S01EA01]
D02149 Epinephrine bitartrate (JAN/USP)
alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
Epinephrine [ATC:A01AD01 B02BC09 C01CA24 R01AA14 R03AA01 S01EA01]
D02149 Epinephrine bitartrate (JAN/USP)
beta1-adrenergic receptor [HSA:153] [KO:K04141]
Epinephrine [ATC:A01AD01 B02BC09 C01CA24 R01AA14 R03AA01 S01EA01]
D02149 Epinephrine bitartrate (JAN/USP)
beta2-adrenergic receptor [HSA:154] [KO:K04142]
Epinephrine [ATC:A01AD01 B02BC09 C01CA24 R01AA14 R03AA01 S01EA01]
D02149 Epinephrine bitartrate (JAN/USP)
beta3-adrenergic receptor [HSA:155] [KO:K04143]
Epinephrine [ATC:A01AD01 B02BC09 C01CA24 R01AA14 R03AA01 S01EA01]
D02149 Epinephrine bitartrate (JAN/USP)
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| Other DBs |
CAS: 51-42-3 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 23
1 C8y C 16.7785 -17.0333
2 C8x C 16.7785 -18.4291
3 C8x C 15.5689 -16.3355
4 C1c C 17.9882 -16.3355
5 C8x C 15.5689 -19.1735
6 C8y C 14.3592 -17.0333
7 C1b C 19.1978 -17.0333
8 O1a O 17.9882 -14.9397
9 C8y C 14.3592 -18.4291
10 N1b N 20.4074 -16.3355
11 O1a O 13.1496 -19.1269
12 O1a O 13.1496 -16.3355
13 C1a C 21.6171 -17.0333
14 O6a O 25.0833 -17.0100
15 C6a C 26.2958 -16.3100
16 C1c C 27.5082 -17.0100
17 C1c C 28.7207 -16.3100
18 C6a C 29.9332 -17.0100
19 O6a O 31.1456 -16.3100
20 O6a O 29.9332 -18.4100
21 O6a O 26.2958 -14.9100
22 O1a O 28.7207 -14.9100
23 O1a O 27.5082 -18.4100
BOND 22
1 1 3 1
2 1 4 1
3 2 5 1
4 3 6 2
5 4 7 1
6 4 8 1 #Up
7 5 9 2
8 7 10 1
9 9 11 1
10 6 9 1
11 6 12 1
12 1 2 2
13 10 13 1
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 18 20 2
20 15 21 2
21 17 22 1 #Up
22 16 23 1 #Up
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