KEGG   DRUG: D02150Help
Entry
D02150                      Drug                                   

Name
l-Isoprenaline hydrochloride (JP16);
Proternol-L (TN)
Formula
C11H17NO3. HCl
Exact mass
247.0975
Mol weight
247.7185
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor agonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA02 Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AB Non-selective beta-adrenoreceptor agonists
     R03AB02 Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CB Non-selective beta-adrenoreceptor agonists
     R03CB01 Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D02150  l-Isoprenaline hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
    beta2-adrenergic receptor
     Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
    beta3-adrenergic receptor
     Isoprenaline
      D02150  l-Isoprenaline hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02150  l-Isoprenaline hydrochloride
BRITE hierarchy
Other DBs
CAS: 
5984-95-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   X   Cl   31.6400  -16.8700
            2   C8y C    21.8400  -16.4500
            3   C8x C    20.6500  -15.6800
            4   C8x C    21.8400  -17.8500
            5   C8y C    19.3900  -16.3800
            6   C8x C    20.5800  -18.4800
            7   C8y C    19.3900  -17.7100
            8   O1a O    18.2000  -15.6100
            9   O1a O    18.2000  -18.4100
            10  C1c C    23.1000  -15.7500
            11  C1b C    24.2900  -16.4500
            12  N1b N    25.4800  -15.7500
            13  C1c C    26.7400  -16.4500
            14  C1a C    27.9300  -15.7500
            15  O1a O    23.1000  -14.3500
            16  C1a C    26.7400  -17.8500
BOND        15
            1     2   3 1
            2     2   4 2
            3     3   5 2
            4     4   6 1
            5     5   7 1
            6     5   8 1
            7     7   9 1
            8     6   7 2
            9     2  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   10  15 1 #Up
            15   13  16 1

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