KEGG   DRUG: D02187Help
Entry
D02187                      Drug                                   

Name
Fosfomycin calcium hydrate (JP16);
Fosmicin (TN)
Formula
C3H5O4P. Ca. H2O
Exact mass
193.9657
Mol weight
194.1364
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Therapeutic category: 
ATC code: 
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor [KO:K00790]
  Pathway
ko00520  Amino sugar and nucleotide sugar metabolism
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6135  Fosfomycins
     D02187  Fosfomycin calcium hydrate (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX01 Fosfomycin
      D02187  Fosfomycin calcium hydrate (JP16)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Fosfomycin
    D02187  Fosfomycin calcium hydrate (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Others
    UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor [KO:K00790]
     Fosfomycin [ATC:J01XX01]
      D02187  Fosfomycin calcium hydrate (JP16)
BRITE hierarchy
Other DBs
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        10
            1   Z   Ca   26.2213  -16.3878 #2+
            2   O0  O    37.8004  -15.7502
            3   C1y C    31.2200  -15.2600
            4   C1y C    32.6200  -15.2600
            5   O2x O    31.9200  -14.0700
            6   P1b P    30.0300  -15.9600
            7   C1a C    33.8100  -15.9600
            8   O1c O    28.7700  -16.6600
            9   O1c O    29.3300  -14.7700 #-
            10  O1c O    30.7300  -17.1500 #-
BOND        8
            1     3   4 1
            2     4   5 1
            3     5   3 1
            4     3   6 1 #Up
            5     4   7 1 #Up
            6     6   8 2
            7     6   9 1
            8     6  10 1

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