KEGG   DRUG: D02192Help
Entry
D02192                      Drug                                   

Name
Saccharin sodium hydrate (JP16);
Saccharin sodium (USP);
Sodium saccharin dihydrate;
Sucaryl (TN)
Formula
C7H4NO3S. 2H2O. Na
Exact mass
241.0021
Mol weight
241.1969
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Sweetener [non-nutritive]
Remark
Therapeutic category: 
Target
taste receptor type 1 member 2 (TAS1R2) agonist [HSA:80834] [KO:K04625];
taste receptor type 1 member 3 (TAS1R3) agonist [HSA:83756] [KO:K04626]
  Pathway
hsa04742  Taste transduction
hsa04973  Carbohydrate digestion and absorption  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 7  Agents not mainly for therapeutic purpose
  71  Dispensing medicines
   714  Flavorings, deodorants, coloring agents
    7149  Others
     D02192  Saccharin sodium hydrate (JP16); Saccharin sodium (USP)
Pharmaceutical additives [BR:br08316]
 Sweetening agent
  D02192  [001272] Saccharin sodium hydrate
 Flavoring substance
  D02192  [001272] Saccharin sodium hydrate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Metabotropic glutamate receptor family
   Chemoreception
    taste receptor type 1
     Saccharin
      D02192  Saccharin sodium hydrate (JP16); Saccharin sodium (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02192  Saccharin sodium hydrate
BRITE hierarchy
Other DBs
CAS: 
6155-57-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        15
            1   C8y C    23.3183  -16.8546
            2   C8y C    23.3122  -18.2504
            3   S2x S    24.6380  -18.6925
            4   N1x N    25.4732  -17.5586 #-
            5   C5x C    24.6551  -16.4245
            6   C8x C    20.8945  -18.2550
            7   C8x C    22.1065  -18.9595
            8   C8x C    22.1099  -16.1533
            9   C8x C    20.8261  -16.8553
            10  O5x O    25.0101  -15.0553
            11  O3c O    23.9389  -19.8969
            12  O3c O    25.8487  -19.3824
            13  O0  O    31.7797  -17.6398
            14  Z   Na   27.2300  -17.6400 #+
            15  O0  O    31.7797  -17.6398
BOND        13
            1     1   2 2
            2     6   7 2
            3     7   2 1
            4     1   8 1
            5     8   9 2
            6     9   6 1
            7     2   3 1
            8     5  10 2
            9     3   4 1
            10    3  11 2
            11    4   5 1
            12    3  12 2
            13    5   1 1
BRACKET     1    29.8900  -18.6200   29.8900  -16.7300
            1    32.4800  -16.7300   32.4800  -18.6200
            1  2
 ORIGINAL  1   13
 REPEAT    1   15

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