KEGG   DRUG: D02195Help
Entry
D02195                      Drug                                   

Name
Mupirocin calcium hydrate (JP16);
Mupirocin calcium (USAN);
Mupirocin calcium dihydrate;
Bactroban (TN)
Product
  Generic
Formula
(C26H43O9)2. 2H2O. Ca
Exact mass
1074.5651
Mol weight
1075.337
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [topical]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
isoleucine tRNA ligase inhibitor, ptotein synthesis inhibitor [KO:K01870]
  Pathway
ko00970  Aminoacyl-tRNA biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX09 Mupirocin
      D02195  Mupirocin calcium hydrate (JP16); Mupirocin calcium (USAN)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AX Other nasal preparations
     R01AX06 Mupirocin
      D02195  Mupirocin calcium hydrate (JP16); Mupirocin calcium (USAN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Mupirocin
    D02195  Mupirocin calcium hydrate (JP16); Mupirocin calcium (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   611  Acting mainly on gram-positive bacteria
    6119  Others
     D02195  Mupirocin calcium hydrate (JP16); Mupirocin calcium (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   isoleucyl-tRNA synthetase (IARS) inhibitor
    Mupirocin
     D02195  Mupirocin calcium hydrate (JP16); Mupirocin calcium (USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02195  Mupirocin calcium hydrate
  D02195  Mupirocin calcium ointment
BRITE hierarchy
Other DBs
CAS: 
115074-43-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        73
            1   Z   Ca   26.4062  -21.9999 #2+
            2   C1y C    23.4532  -16.6787
            3   C1y C    23.4532  -18.0836
            4   C1x C    24.6667  -18.7824
            5   O2x O    25.8803  -18.0836
            6   C1y C    25.8803  -16.6787
            7   C1y C    24.6667  -15.9726
            8   C1y C    21.0316  -18.0907
            9   C1b C    22.2461  -18.7967
            10  O1a O    22.2408  -15.9833
            11  O1a O    24.6533  -14.5676
            12  C1b C    27.0892  -15.9726
            13  C2c C    28.3034  -16.6646
            14  C2b C    29.5178  -15.9657
            15  C7a C    30.7321  -16.6575
            16  O7a O    31.9395  -15.9585
            17  C1b C    33.1537  -16.6504
            18  C1b C    34.3681  -15.9514
            19  C1b C    35.5824  -16.6434
            20  C1b C    36.7966  -15.9445
            21  C1b C    38.0110  -16.6363
            22  C1b C    39.2254  -15.9374
            23  C1b C    40.4396  -16.6292
            24  C1b C    41.6469  -15.9302
            25  C6a C    42.8613  -16.6222
            26  O6a O    44.0757  -15.9162 #-
            27  C1a C    28.3065  -18.0695
            28  O6a O    30.7352  -18.0624
            29  O6a O    42.8674  -18.0272
            30  C1y C    19.8131  -18.7951
            31  C1c C    18.5962  -18.0878
            32  C1c C    17.3778  -18.7922
            33  C1a C    16.1609  -18.0849
            34  O2x O    21.0528  -19.4320
            35  O1a O    17.3761  -20.1972
            36  C1a C    18.5979  -16.6829
            37  O0  O    34.2096  -22.1025
            38  C1y C    23.4532  -16.6787
            39  O1a O    22.2408  -15.9833
            40  C1y C    23.4532  -18.0836
            41  C1b C    22.2461  -18.7967
            42  C1y C    21.0316  -18.0907
            43  O2x O    21.0528  -19.4320
            44  C1y C    19.8131  -18.7951
            45  C1c C    18.5962  -18.0878
            46  C1a C    18.5979  -16.6829
            47  C1c C    17.3778  -18.7922
            48  C1a C    16.1609  -18.0849
            49  O1a O    17.3761  -20.1972
            50  C1x C    24.6667  -18.7824
            51  O2x O    25.8803  -18.0836
            52  C1y C    25.8803  -16.6787
            53  C1y C    24.6667  -15.9726
            54  O1a O    24.6533  -14.5676
            55  C1b C    27.0892  -15.9726
            56  C2c C    28.3034  -16.6646
            57  C2b C    29.5178  -15.9657
            58  C7a C    30.7321  -16.6575
            59  O7a O    31.9395  -15.9585
            60  C1b C    33.1537  -16.6504
            61  C1b C    34.3681  -15.9514
            62  C1b C    35.5824  -16.6434
            63  C1b C    36.7966  -15.9445
            64  C1b C    38.0110  -16.6363
            65  C1b C    39.2254  -15.9374
            66  C1b C    40.4396  -16.6292
            67  C1b C    41.6469  -15.9302
            68  C6a C    42.8613  -16.6222
            69  O6a O    44.0757  -15.9162 #-
            70  O6a O    42.8674  -18.0272
            71  O6a O    30.7352  -18.0624
            72  C1a C    28.3065  -18.0695
            73  O0  O    34.2096  -22.1025
BOND        72
            1    32  33 1
            2     4   5 1
            3     8  34 1 #Up
            4    30  34 1 #Up
            5     5   6 1
            6    32  35 1 #Up
            7     6   7 1
            8    31  36 1 #Down
            9     8   9 1
            10    3   9 1 #Down
            11    2  10 1 #Up
            12    7  11 1 #Up
            13    6  12 1 #Down
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   13  27 1
            29   15  28 2
            30   25  29 2
            31    8  30 1
            32    2   3 1
            33   30  31 1
            34    2   7 1
            35   31  32 1
            36    3   4 1
            37   47  48 1
            38   50  51 1
            39   42  43 1 #Up
            40   44  43 1 #Up
            41   51  52 1
            42   47  49 1 #Up
            43   52  53 1
            44   45  46 1 #Down
            45   42  41 1
            46   40  41 1 #Down
            47   38  39 1 #Up
            48   53  54 1 #Up
            49   52  55 1 #Down
            50   55  56 1
            51   56  57 2
            52   57  58 1
            53   58  59 1
            54   59  60 1
            55   60  61 1
            56   61  62 1
            57   62  63 1
            58   63  64 1
            59   64  65 1
            60   65  66 1
            61   66  67 1
            62   67  68 1
            63   68  69 1
            64   56  72 1
            65   58  71 2
            66   68  70 2
            67   42  44 1
            68   38  40 1
            69   44  45 1
            70   38  53 1
            71   45  47 1
            72   40  50 1
BRACKET     1    14.4200  -20.6500   14.4200  -14.1400
            1    45.0800  -14.1400   45.0800  -20.6500
            1  2
 ORIGINAL  1    2  10   3   9   8  34  30  31  36  32  33  35   4   5   6   7
            1   11  12  13  14  15  16  17  18  19  20  21  22  23  24  25  26
            1   29  28  27
 REPEAT    1   38  39  40  41  42  43  44  45  46  47  48  49  50  51  52  53
            1   54  55  56  57  58  59  60  61  62  63  64  65  66  67  68  69
            1   70  71  72
            2    31.9200  -23.0300   31.9200  -21.2100
            2    35.0000  -21.2100   35.0000  -23.0300
            2  2
 ORIGINAL  2   37
 REPEAT    2   73

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