KEGG   DRUG: D02226Help
Entry
D02226                      Drug                                   

Name
Cefazolin sodium hydrate (JP16)
Formula
C14H13N8O4S3. 5H2O. Na
Exact mass
566.0648
Mol weight
566.5654
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB04 Cefazolin
      D02226  Cefazolin sodium hydrate (JP16)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefazolin
    D02226  Cefazolin sodium hydrate (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D02226  Cefazolin sodium hydrate (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefazolin
      D02226  Cefazolin sodium hydrate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02226  Cefazolin sodium hydrate
BRITE hierarchy
Other DBs
CAS: 
115850-11-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        35
            1   C1y C    18.0487  -14.7849
            2   N1y N    18.0487  -16.1806
            3   C2y C    19.2576  -16.8783
            4   C2y C    20.4663  -16.1806
            5   C1x C    20.4663  -14.7849
            6   S2x S    19.2576  -14.0870
            7   C1y C    16.6529  -14.7849
            8   C5x C    16.6529  -16.1806
            9   N1b N    15.4443  -14.0870
            10  C5a C    14.2354  -14.7849
            11  O5a O    14.2354  -16.1806
            12  O5x O    15.4443  -16.8783
            13  C1b C    13.0266  -14.0870
            14  C1b C    21.6935  -16.8895
            15  C6a C    19.2576  -18.2739
            16  O6a O    18.0319  -18.9816
            17  O6a O    20.4493  -18.9621 #-
            18  N4y N    11.7985  -14.7965
            19  S2a S    22.9071  -16.1890
            20  C8y C    24.1155  -16.8870
            21  N5x N    24.5393  -18.2151
            22  N5x N    25.9360  -18.2265
            23  C8y C    26.3784  -16.9017
            24  S2x S    25.2552  -16.0715
            25  C1a C    27.7744  -16.8829
            26  C8x C    10.6469  -13.9856
            27  N5x N     9.5153  -14.8305
            28  N5x N     9.9690  -16.1679
            29  N5x N    11.3811  -16.1498
            30  Z   Na   21.9094  -18.8997 #+
            31  O0  O    25.6200  -14.2800
            32  O0  O    25.6200  -14.2800
            33  O0  O    25.6200  -14.2800
            34  O0  O    25.6200  -14.2800
            35  O0  O    25.6200  -14.2800
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   14  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   20  24 1
            27   23  25 1
            28   18  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   18  29 1
BRACKET     1    23.5200  -14.9100   23.5200  -13.5100
            1    26.1100  -13.5100   26.1100  -14.9100
            1  5
 ORIGINAL  1   32
 REPEAT    1   33  34  35  36

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