KEGG   DRUG: Cefazolin sodium hydrateHelp
Entry
D02226                      Drug                                   

Name
Cefazolin sodium hydrate (JP17)
Formula
C14H13N8O4S3. 5H2O. Na
Exact mass
566.0648
Mol weight
566.5654
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01774  First-generation cephalosporin
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antibacterial, Cell wall biosynthesis inhibitor
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding protein
  Pathway
Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB04 Cefazolin
      D02226  Cefazolin sodium hydrate (JP17)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefazolin
    D02226  Cefazolin sodium hydrate (JP17)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D02226  Cefazolin sodium hydrate (JP17)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephem
     First-generation cephalosporin
      Cefazolin
       D02226  Cefazolin sodium hydrate (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02226  Cefazolin sodium hydrate
Antibacterials [br08350.html]
 D02226
BRITE hierarchy
Other DBs
CAS: 
115850-11-8
PubChem: 
ChEBI: 
LigandBox: 
KCF data Show

ATOM        35
            1   C1y C    18.0487  -14.7849
            2   N1y N    18.0487  -16.1806
            3   C2y C    19.2576  -16.8783
            4   C2y C    20.4663  -16.1806
            5   C1x C    20.4663  -14.7849
            6   S2x S    19.2576  -14.0870
            7   C1y C    16.6529  -14.7849
            8   C5x C    16.6529  -16.1806
            9   N1b N    15.4443  -14.0870
            10  C5a C    14.2354  -14.7849
            11  O5a O    14.2354  -16.1806
            12  O5x O    15.4443  -16.8783
            13  C1b C    13.0266  -14.0870
            14  C1b C    21.6935  -16.8895
            15  C6a C    19.2576  -18.2739
            16  O6a O    18.0319  -18.9816
            17  O6a O    20.4493  -18.9621 #-
            18  N4y N    11.7985  -14.7965
            19  S2a S    22.9071  -16.1890
            20  C8y C    24.1155  -16.8870
            21  N5x N    24.5393  -18.2151
            22  N5x N    25.9360  -18.2265
            23  C8y C    26.3784  -16.9017
            24  S2x S    25.2552  -16.0715
            25  C1a C    27.7744  -16.8829
            26  C8x C    10.6469  -13.9856
            27  N5x N     9.5153  -14.8305
            28  N5x N     9.9690  -16.1679
            29  N5x N    11.3811  -16.1498
            30  Z   Na   21.9094  -18.8997 #+
            31  O0  O    25.6200  -14.2800
            32  O0  O    25.6200  -14.2800
            33  O0  O    25.6200  -14.2800
            34  O0  O    25.6200  -14.2800
            35  O0  O    25.6200  -14.2800
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   14  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   20  24 1
            27   23  25 1
            28   18  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   18  29 1
BRACKET     1    23.5200  -14.9100   23.5200  -13.5100
            1    26.1100  -13.5100   26.1100  -14.9100
            1  5
 ORIGINAL  1   32
 REPEAT    1   33  34  35  36

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