| Entry |
|
|---|
| Name |
Cefozopran hydrochloride (JP16);
CZOP;
Firstcin (TN)
|
|---|
| Formula |
C19H18N9O5S2. Cl
|
|---|
| Exact mass |
551.0561
|
|---|
| Mol weight |
551.9865
|
|---|
| Structure |
     |
|---|
| Activity |
Antibiotic
|
|---|
| Remark |
Therapeutic category: ATC code: |
|---|
| Comment |
Semisynthetic cephalosporin: broad spectrum cephalosporin
|
|---|
| Target |
penicillin binding proteins inhibitor |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D02233 Cefozopran hydrochloride (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DE Fourth-generation cephalosporins
J01DE03 Cefozopran
D02233 Cefozopran hydrochloride (JP16)
Antiinfectives [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor
Penicillin binding proteins inhibitor
Cephems - Cephalosporins
Cefozopran [ATC:J01DE03]
D02233 Cefozopran hydrochloride (JP16)
 |
|---|
| Other DBs |
CAS: 113981-44-5 PubChem: LigandBox: |
|---|
| KCF data |
ATOM 36
1 C1y C 25.4311 -18.8403
2 N1y N 25.4311 -20.2356
3 C2y C 26.6170 -20.9333
4 C2y C 27.8031 -20.2356
5 C1x C 27.8031 -18.8403
6 S2x S 26.6170 -18.1426
7 C1y C 24.0357 -18.8403
8 C5x C 24.0357 -20.2356
9 N1b N 22.7799 -18.1426
10 C5a C 21.5940 -18.8403
11 O5a O 21.5940 -20.2356
12 O5x O 22.7799 -20.9333
13 C2c C 20.4079 -18.1426
14 C1b C 29.0589 -20.9333
15 C8y C 19.1521 -18.8403
16 N5y N 30.2450 -20.2356 #+
17 N5x N 18.1056 -18.0030
18 S2x S 16.9196 -18.7705
19 C8y C 17.3382 -20.1658
20 N5x N 18.7334 -20.1658
21 N2b N 20.4079 -16.7472
22 C6a C 26.6170 -22.3286
23 O6a O 27.8031 -23.0263
24 O6a O 25.3613 -23.0263
25 N1a N 16.5010 -21.2820
26 C8y C 31.3910 -21.0359
27 N4y N 32.5074 -20.1960
28 C8x C 32.0536 -18.8747
29 C8x C 30.6567 -18.8980
30 C8x C 31.3910 -22.4309
31 C8x C 32.5873 -23.1224
32 C8x C 33.8268 -22.4078
33 N5x N 33.8268 -21.0128
34 O2a O 21.6548 -16.0340
35 C1a C 21.6605 -14.6303
36 X Cl 30.0299 -17.7099 #-
BOND 39
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 14 16 1
18 15 17 2
19 17 18 1
20 18 19 1
21 19 20 2
22 15 20 1
23 13 21 2
24 3 22 1
25 22 23 1
26 22 24 2
27 19 25 1
28 16 26 2
29 26 27 1
30 27 28 1
31 28 29 2
32 16 29 1
33 26 30 1
34 30 31 2
35 31 32 1
36 32 33 2
37 33 27 1
38 21 34 1
39 34 35 1
|
|---|
