KEGG   DRUG: D02246Help
Entry
D02246                      Drug                                   

Name
Biperiden hydrochloride (JP16/USP);
Tasmolin (TN)
Formula
C21H29NO. HCl
Exact mass
347.2016
Mol weight
347.922
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic;
Antiparkinsonian
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
centrally active anticholinergic drugs
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D02246  Biperiden hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1162  Biperidens
     D02246  Biperiden hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Biperiden
      D02246  Biperiden hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02246  Biperiden hydrochloride
BRITE hierarchy
Other DBs
CAS: 
1235-82-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   X   Cl   28.7000  -22.4700
            2   C1y C    21.8400  -20.9300
            3   C1d C    21.8400  -22.3300
            4   C1y C    23.1000  -20.2300
            5   C1x C    20.6500  -20.2300
            6   C8y C    23.1000  -23.0300
            7   C1b C    20.6500  -23.0300
            8   C1x C    22.1200  -19.2500
            9   C2x C    23.1000  -18.8300
            10  C1y C    20.6500  -18.8300
            11  C8x C    23.1000  -24.4300
            12  C8x C    24.2900  -22.3300
            13  C1b C    19.4600  -22.3300
            14  C2x C    21.9100  -18.1300
            15  C8x C    24.2200  -25.1300
            16  C8x C    25.4800  -23.1000
            17  N1y N    18.2000  -23.0300
            18  C8x C    25.4800  -24.4300
            19  C1x C    18.2000  -24.4300
            20  C1x C    17.0100  -22.3300
            21  C1x C    17.0100  -25.0600
            22  C1x C    15.8200  -23.0300
            23  C1x C    15.8200  -24.3600
            24  O1a O    23.0524  -21.6300
BOND        26
            1     2   3 1
            2     2   4 1
            3     2   5 1
            4     3   6 1
            5     3   7 1
            6     4   8 1
            7     4   9 1
            8     5  10 1
            9     6  11 1
            10    6  12 2
            11    7  13 1
            12    9  14 2
            13   11  15 2
            14   12  16 1
            15   13  17 1
            16   15  18 1
            17   17  19 1
            18   17  20 1
            19   19  21 1
            20   20  22 1
            21   21  23 1
            22    8  10 1
            23   10  14 1
            24   16  18 2
            25   22  23 1
            26    3  24 1

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