KEGG   DRUG: D02247Help
Entry
D02247                      Drug                                   

Name
Biperiden lactate (JAN/USP);
Tasmolin (TN)
Formula
C21H29NO. C3H6O3
Exact mass
401.2566
Mol weight
401.539
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic;
Antiparkinsonian
Remark
Therapeutic category: 
ATC code: 
Comment
centrally active anticholinergic drugs
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1162  Biperidens
     D02247  Biperiden lactate (JAN/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D02247  Biperiden lactate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Biperiden [ATC:N04AA02]
      D02247  Biperiden lactate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
7085-45-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   O1a O    26.1800  -22.4700
            2   C1c C    27.4400  -23.1700
            3   C6a C    28.6300  -22.4700
            4   O6a O    29.8200  -23.1700
            5   C1a C    27.4400  -24.5700
            6   O6a O    28.6300  -21.0700
            7   C1y C    20.7900  -20.9300
            8   C1d C    20.7900  -22.3300
            9   C1y C    22.0500  -20.2300
            10  C1x C    19.6000  -20.2300
            11  C8y C    22.0500  -23.0300
            12  C1b C    19.6000  -23.0300
            13  C1x C    21.0700  -19.2500
            14  C2x C    22.0500  -18.8300
            15  C1y C    19.6700  -18.8300
            16  C8x C    22.0500  -24.4300
            17  C8x C    23.2400  -22.3300
            18  C1b C    18.4100  -22.3300
            19  C2x C    20.8600  -18.1300
            20  C8x C    23.1700  -25.1300
            21  C8x C    24.4300  -23.0300
            22  N1y N    17.1500  -23.0300
            23  C8x C    24.4300  -24.4300
            24  C1x C    17.1500  -24.3600
            25  C1x C    15.9600  -22.3300
            26  C1x C    15.9600  -25.0600
            27  C1x C    14.7700  -23.0300
            28  C1x C    14.7700  -24.3600
            29  O1a O    22.0024  -21.6300
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     2   5 1
            5     3   6 2
            6     7   8 1
            7     7   9 1
            8     7  10 1
            9     8  11 1
            10    8  12 1
            11    9  13 1
            12    9  14 1
            13   10  15 1
            14   11  16 1
            15   11  17 2
            16   12  18 1
            17   14  19 2
            18   16  20 2
            19   17  21 1
            20   18  22 1
            21   20  23 1
            22   22  24 1
            23   22  25 1
            24   24  26 1
            25   25  27 1
            26   26  28 1
            27   13  15 1
            28   15  19 1
            29   21  23 2
            30   27  28 1
            31    8  29 1

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