KEGG   DRUG: D02253Help
Entry
D02253                      Drug                                   

Name
Pentobarbital calcium (JP16);
Ravona (TN)
Formula
(C11H17N2O3)2. Ca
Exact mass
490.2104
Mol weight
490.6066
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Sedative-hypnotic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Barbiturates
Target
GABAA-receptor (picrotoxin binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Structure map
Hypnotics
GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CA Barbiturates, plain
     N05CA01 Pentobarbital
      D02253  Pentobarbital calcium (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1125  Barbiturates and thiobarbiturates
     D02253  Pentobarbital calcium (JP16)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (picrotoxin binding site)
     Pentobarbital
      D02253  Pentobarbital calcium (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02253  Pentobarbital calcium
BRITE hierarchy
Other DBs
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        33
            1   C1z C    24.7724  -19.2210
            2   C5x C    24.7724  -20.6370
            3   C5x C    23.5779  -18.5394
            4   C1c C    26.1651  -19.2153
            5   C1b C    24.7607  -17.8109
            6   N1x N    23.5779  -21.3361
            7   O5x O    25.9902  -21.3361
            8   N2x N    22.3544  -19.2210
            9   O5x O    23.5779  -17.1409
            10  C1b C    26.8526  -18.0032
            11  C1a C    26.8641  -20.4272
            12  C1a C    25.9728  -17.1001
            13  C2y C    22.3544  -20.6370
            14  C1b C    28.2451  -18.0032
            15  O1a O    21.1366  -21.3361 #-
            16  C1a C    28.9444  -16.7913
            17  Z   Ca   17.9293  -21.4003 #2+
            18  C1z C    24.7724  -19.2210
            19  C5x C    24.7724  -20.6370
            20  N1x N    23.5779  -21.3361
            21  C2y C    22.3544  -20.6370
            22  N2x N    22.3544  -19.2210
            23  C5x C    23.5779  -18.5394
            24  O5x O    23.5779  -17.1409
            25  O1a O    21.1366  -21.3361 #-
            26  O5x O    25.9902  -21.3361
            27  C1c C    26.1651  -19.2153
            28  C1b C    26.8526  -18.0032
            29  C1b C    28.2451  -18.0032
            30  C1a C    28.9444  -16.7913
            31  C1a C    26.8641  -20.4272
            32  C1b C    24.7607  -17.8109
            33  C1a C    25.9728  -17.1001
BOND        32
            1    14  16 1
            2     8  13 2
            3     1   2 1
            4     1   3 1
            5     1   4 1
            6     1   5 1
            7     2   6 1
            8     2   7 2
            9     3   8 1
            10    3   9 2
            11    4  10 1
            12    4  11 1
            13    5  12 1
            14    6  13 1
            15   10  14 1
            16   13  15 1
            17   29  30 1
            18   22  21 2
            19   18  19 1
            20   18  23 1
            21   18  27 1
            22   18  32 1
            23   19  20 1
            24   19  26 2
            25   23  22 1
            26   23  24 2
            27   27  28 1
            28   27  31 1
            29   32  33 1
            30   20  21 1
            31   28  29 1
            32   21  25 1
BRACKET     1    20.3000  -22.4000   20.3000  -16.0300
            1    30.5200  -16.0300   30.5200  -22.4000
            1  2
 ORIGINAL  1    1   2   6  13   8   3   9  15   7   4  10  14  16  11   5  12
 REPEAT    1   18  19  20  21  22  23  24  25  26  27  28  29  30  31  32  33

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