KEGG   DRUG: D02267Help
Entry
D02267                      Drug                                   

Name
Foscarnet sodium hydrate (JAN);
Trisodium phosphonoformate hexahydrate;
Foscavir (TN)
Formula
CO5P. 6H2O. 3Na
Exact mass
299.981
Mol weight
300.0424
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00368]
Remark
Therapeutic category: 
ATC code: 
Target
DNA polymerase inhibitor [EC:2.7.7.7]
Interaction
Drug interaction
Structure map
Antiviral agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D02267  Foscarnet sodium hydrate (JAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AD Phosphonic acid derivatives
     J05AD01 Foscarnet
      D02267  Foscarnet sodium hydrate (JAN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-cytomegalovirus (CMV) Agents
   Foscarnet
    D02267  Foscarnet sodium hydrate (JAN)
  Antiherpetic Agents
   Foscarnet
    D02267  Foscarnet sodium hydrate (JAN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-CMV agent
   DNA polymerase inhibitor
    Phosphonic acid derivatives
     Foscarnet [ATC:J05AD01]
      D02267  Foscarnet sodium hydrate (JAN)
BRITE hierarchy
Other DBs
CAS: 
34156-56-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   O0  O    35.4900  -21.2800
            2   Z   Na   26.7400  -23.1000 #+
            3   Z   Na   31.0100  -21.8400 #+
            4   Z   Na   24.1500  -20.5800 #+
            5   P1b P    27.3700  -20.5800
            6   C6a C    28.7700  -20.5800
            7   O1c O    27.3700  -21.9800 #-
            8   O1c O    25.9700  -20.5800 #-
            9   O1c O    27.3700  -19.1800
            10  O6a O    29.4700  -21.8400 #-
            11  O6a O    29.4700  -19.3900
            12  O0  O    35.4900  -21.2800
            13  O0  O    35.4900  -21.2800
            14  O0  O    35.4900  -21.2800
            15  O0  O    35.4900  -21.2800
            16  O0  O    35.4900  -21.2800
BOND        6
            1     5   7 1
            2     5   8 1
            3     5   9 2
            4     6  10 1
            5     5   6 1
            6     6  11 2
BRACKET     1    33.4600  -22.1200   33.4600  -20.4400
            1    35.9800  -20.4400   35.9800  -22.1200
            1  6
 ORIGINAL  1    1
 REPEAT    1   12  13  14  15  16

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