KEGG   DRUG: D02283Help
Entry
D02283                      Drug                                   
Name
Iomazenil (123I) (JAN/INN);
Benzodine (TN)
Formula
C15H14IN3O3
Exact mass
407.0091
Mol weight
411.1944
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
Comment
benzodiazepine derivative
Target
GABAA-receptor (benzodiazepine binding site) antagonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  43  Radioactive drugs
   430  Radioactive drugs
    4300  Radioactive drugs
     D02283  Iomazenil (123I) (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site) [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05176 K05177 K05178 K05179 K05180 K05181 K05182 K05183 K05184 K05185 K05186 K05187 K05188 K05189 K05192]
     Iomazenil
      D02283  Iomazenil (123I) (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
127396-36-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C5x C    10.9834  -11.4194
            2   C8y C    10.1413  -10.3098
            3   C8y C    10.4765   -8.9530
            4   N4y N    11.7375   -8.3749
            5   N1y N    12.3892  -11.4446
            6   C8y C    12.9911   -8.9972
            7   C1x C    13.2776  -10.3659
            8   C8x C     9.4694   -7.9846
            9   C8x C     8.1274   -8.3727
            10  C8x C     7.7922   -9.7295
            11  C8y C     8.7993  -10.6976
            12  O5x O    10.3489  -12.6691
            13  C1a C    12.9625  -12.6876
            14  X   I     8.4618  -12.0634
            15  C8y C    13.9704   -7.9973
            16  N5x N    13.3220   -6.7570
            17  C8x C    11.9420   -6.9904
            18  C7a C    15.3816   -7.9962
            19  O7a O    16.0802   -9.2037
            20  O6a O    16.0921   -6.7630
            21  C1b C    17.4996   -9.2029
            22  C1a C    18.1863  -10.3902
BOND        24
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    1  12 2
            14    5  13 1
            15   11  14 1
            16    6  15 2
            17   15  16 1
            18   16  17 2
            19    4  17 1
            20   15  18 1
            21   18  19 1
            22   18  20 2
            23   19  21 1
            24   21  22 1

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