KEGG   DRUG: Pefloxacin mesylateHelp
Entry
D02307                      Drug                                   

Name
Pefloxacin mesylate (USAN)
Formula
C17H20FN3O3. CH4SO3
Exact mass
429.137
Mol weight
429.4631
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA03 Pefloxacin
      D02307  Pefloxacin mesylate (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Pefloxacin
      D02307  Pefloxacin mesylate (USAN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP1A2
   Pefloxacin
    D02307  Pefloxacin mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
70458-95-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C8y C    20.0392  -16.5394
            2   C8y C    20.0392  -15.1398
            3   C8x C    18.8263  -14.4401
            4   C8y C    17.6134  -15.1398
            5   C8y C    17.6134  -16.5394
            6   C8x C    18.8263  -17.2391
            7   N4y N    21.2522  -17.2391
            8   C8x C    22.4651  -16.5394
            9   C8y C    22.4651  -15.1398
            10  C8y C    21.2522  -14.4401
            11  O5x O    21.2522  -13.0405
            12  C6a C    23.6780  -14.4401
            13  O6a O    24.8910  -15.1398
            14  O6a O    23.6780  -13.0405
            15  X   F    16.4005  -14.4401
            16  N1y N    16.4005  -17.2391
            17  C1x C    15.1876  -16.5394
            18  C1x C    13.9747  -17.2391
            19  N1y N    13.9747  -18.6387
            20  C1x C    15.1876  -19.3384
            21  C1x C    16.4005  -18.6387
            22  C1a C    12.7617  -19.3384
            23  C1b C    21.2522  -18.6387
            24  C1a C    20.0392  -19.3384
            25  S4a S    30.1625  -16.3994
            26  O1d O    31.5621  -16.3994
            27  C1a C    28.7630  -16.3994
            28  O1d O    30.1625  -14.9999
            29  O1d O    30.1625  -17.7990
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    2  10 1
            12   10  11 2
            13    9  12 1
            14   12  13 1
            15   12  14 2
            16    4  15 1
            17    5  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   16  21 1
            24   19  22 1
            25    7  23 1
            26   23  24 1
            27   25  26 1
            28   25  27 1
            29   25  28 2
            30   25  29 2

» Japanese version   » Back

DBGET integrated database retrieval system