KEGG   DRUG: TosufloxacinHelp
Entry
D02317                      Drug                                   

Name
Tosufloxacin (USAN);
TFLX
Formula
C19H15F3N4O3
Exact mass
404.1096
Mol weight
404.3426
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Tosufloxacin
      D02317  Tosufloxacin (USAN)
BRITE hierarchy
Other DBs
CAS: 
100490-36-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C8y C    22.6649  -14.7751
            2   N4y N    23.8789  -15.4754
            3   C8y C    22.6649  -13.3743
            4   N5x N    21.4509  -15.4754
            5   C8y C    23.8789  -16.8762
            6   C8x C    25.0929  -14.7751
            7   C8y C    23.8322  -12.6739
            8   C8x C    21.4509  -12.6739
            9   C8y C    20.2369  -14.7751
            10  C8y C    25.0929  -17.5298
            11  C8x C    22.6649  -17.5298
            12  C8y C    25.0929  -13.3743
            13  O5x O    23.8322  -11.2732
            14  C8y C    20.2369  -13.3743
            15  N1y N    19.0230  -15.5222
            16  C8x C    25.0929  -18.9773
            17  X   F    26.2602  -16.8762
            18  C8x C    22.6649  -18.9306
            19  C6a C    26.2135  -12.6739
            20  X   F    19.0230  -12.6739
            21  C8y C    23.8789  -19.6310
            22  O6a O    27.4275  -13.3743
            23  O6a O    26.2135  -11.2732
            24  X   F    23.8789  -21.0784
            25  C1x C    17.7156  -14.9619
            26  C1x C    16.8284  -16.0357
            27  C1y C    17.5755  -17.2031
            28  C1x C    19.0230  -16.8762
            29  N1a N    17.0152  -18.5104
BOND        32
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    6  12 2
            12    7  13 2
            13    8  14 2
            14    9  15 1
            15   10  16 1
            16   10  17 1
            17   11  18 2
            18   12  19 1
            19   14  20 1
            20   16  21 2
            21   19  22 1
            22   19  23 2
            23   21  24 1
            24    7  12 1
            25    9  14 1
            26   18  21 1
            27   15  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   15  28 1
            32   27  29 1

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