KEGG   DRUG: LomefloxacinHelp
Entry
D02318                      Drug                                   

Name
Lomefloxacin (USAN);
LFLX
Formula
C17H19F2N3O3
Exact mass
351.1394
Mol weight
351.3479
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA07 Lomefloxacin
      D02318  Lomefloxacin (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE04 Lomefloxacin
      D02318  Lomefloxacin (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Lomefloxacin
      D02318  Lomefloxacin (USAN)
BRITE hierarchy
Other DBs
CAS: 
98079-51-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8y C    22.6826  -15.8502
            2   C8y C    22.6826  -14.4430
            3   N4y N    23.9491  -16.5538
            4   C8y C    21.4631  -16.5538
            5   C8y C    23.9491  -13.7394
            6   C8x C    21.4631  -13.7394
            7   C8x C    25.1687  -15.8502
            8   C1b C    23.9491  -17.9140
            9   C8y C    20.2904  -15.8970
            10  X   F    21.4631  -17.9140
            11  C8y C    25.1687  -14.4430
            12  O5x O    23.9491  -12.3322
            13  C8y C    20.2904  -14.4898
            14  N1y N    19.0709  -16.6006
            15  C6a C    26.3883  -13.7394
            16  X   F    19.0709  -13.8332
            17  C1x C    19.0709  -17.9610
            18  C1x C    17.8513  -15.9439
            19  O6a O    26.3883  -12.3322
            20  O6a O    27.6078  -14.4430
            21  C1y C    17.8513  -18.7114
            22  C1x C    16.6317  -16.6475
            23  N1x N    16.6317  -18.0078
            24  C1a C    17.8513  -20.1186
            25  C1a C    22.7296  -18.6176
BOND        27
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 2
            12    6  13 2
            13    9  14 1
            14   11  15 1
            15   13  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 2
            19   15  20 1
            20   17  21 1
            21   18  22 1
            22   21  23 1
            23   21  24 1
            24    7  11 2
            25    9  13 1
            26   22  23 1
            27    8  25 1

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