KEGG   DRUG: D02318Help
Entry
D02318                      Drug                                   

Name
Lomefloxacin (USAN);
LFLX
Formula
C17H19F2N3O3
Exact mass
351.1394
Mol weight
351.3479
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Target
DNA gyrase inhibitor [KO:K02469 K02470];
topoisomerase IV inhibitor [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA07 Lomefloxacin
      D02318  Lomefloxacin (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE04 Lomefloxacin
      D02318  Lomefloxacin (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Lomefloxacin
      D02318  Lomefloxacin (USAN)
BRITE hierarchy
Other DBs
CAS: 
98079-51-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8y C    22.6826  -15.8502
            2   C8y C    22.6826  -14.4430
            3   N4y N    23.9491  -16.5538
            4   C8y C    21.4631  -16.5538
            5   C8y C    23.9491  -13.7394
            6   C8x C    21.4631  -13.7394
            7   C8x C    25.1687  -15.8502
            8   C1b C    23.9491  -17.9140
            9   C8y C    20.2904  -15.8970
            10  X   F    21.4631  -17.9140
            11  C8y C    25.1687  -14.4430
            12  O5x O    23.9491  -12.3322
            13  C8y C    20.2904  -14.4898
            14  N1y N    19.0709  -16.6006
            15  C6a C    26.3883  -13.7394
            16  X   F    19.0709  -13.8332
            17  C1x C    19.0709  -17.9610
            18  C1x C    17.8513  -15.9439
            19  O6a O    26.3883  -12.3322
            20  O6a O    27.6078  -14.4430
            21  C1y C    17.8513  -18.7114
            22  C1x C    16.6317  -16.6475
            23  N1x N    16.6317  -18.0078
            24  C1a C    17.8513  -20.1186
            25  C1a C    22.7296  -18.6176
BOND        27
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 2
            12    6  13 2
            13    9  14 1
            14   11  15 1
            15   13  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 2
            19   15  20 1
            20   17  21 1
            21   18  22 1
            22   21  23 1
            23   21  24 1
            24    7  11 2
            25    9  13 1
            26   22  23 1
            27    8  25 1

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