KEGG   DRUG: D02342Help
Entry
D02342                      Drug                                   

Name
Bisoprolol (JAN/USAN/INN)
Formula
C18H31NO4
Exact mass
325.2253
Mol weight
325.443
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive [beta-blocker]
Remark
Same as: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB07 Bisoprolol
      D02342  Bisoprolol (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Bisoprolol
    D02342  Bisoprolol (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bisoprolol
      D02342  Bisoprolol (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
66722-44-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C    22.1200  -14.8400
            2   C8x C    23.3800  -15.5400
            3   C8x C    20.9300  -15.5400
            4   O2a O    22.1200  -13.4400
            5   C8x C    23.3800  -16.9400
            6   C8x C    20.9300  -16.9400
            7   C1b C    23.3100  -12.7400
            8   C8y C    22.1200  -17.6400
            9   C1c C    24.5700  -13.4400
            10  C1b C    22.1200  -19.0400
            11  C1b C    25.7600  -12.7400
            12  O1a O    24.5700  -14.8400
            13  O2a O    20.9300  -19.7400
            14  N1b N    26.9500  -13.4400
            15  C1b C    19.7400  -18.9700
            16  C1c C    28.2100  -12.7400
            17  C1b C    18.4800  -19.7400
            18  C1a C    29.4000  -13.4400
            19  C1a C    28.2100  -11.2700
            20  O2a O    17.2900  -18.9700
            21  C1c C    16.1000  -19.6700
            22  C1a C    14.8400  -18.9700
            23  C1a C    16.1000  -21.1400
BOND        23
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   14  16 1
            16   15  17 1
            17   16  18 1
            18   16  19 1
            19   17  20 1
            20   20  21 1
            21   21  22 1
            22   21  23 1
            23    6   8 2

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