KEGG   DRUG: D02346Help
Entry
D02346                      Drug                                   

Name
Lincomycin hydrochloride hydrate (JP16/USP);
LCM;
Lincocin (TN)
Product
Formula
C18H34N2O6S. HCl. H2O
Exact mass
460.201
Mol weight
461.0136
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic lincosamide
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FF Lincosamides
     J01FF02 Lincomycin
      D02346  Lincomycin hydrochloride hydrate (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Lincomycin
    D02346  Lincomycin hydrochloride hydrate (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   611  Acting mainly on gram-positive bacteria
    6112  Lincomycins
     D02346  Lincomycin hydrochloride hydrate (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor
    Lincosamides
     Lincomycin
      D02346  Lincomycin hydrochloride hydrate (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02346  Lincomycin hydrochloride hydrate
  D02346  Lincomycin hydrochloride injection
BRITE hierarchy
Other DBs
CAS: 
7179-49-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   X   Cl   42.2026  -19.1151
            2   O0  O    45.2623  -19.1151
            3   C1y C    33.7529  -17.8570
            4   C1c C    32.5531  -17.1614
            5   O2x O    34.9700  -17.1614
            6   C1y C    33.7529  -19.2480
            7   N1b N    31.3475  -17.8570
            8   C1c C    32.5415  -15.4923
            9   C1y C    36.1698  -17.8570
            10  C1y C    34.9700  -19.9436
            11  O1a O    32.5531  -19.9493
            12  C5a C    30.1363  -17.1673
            13  C1a C    33.7356  -14.7851
            14  O1a O    31.3300  -14.8026
            15  C1y C    36.1698  -19.2480
            16  S2a S    37.3813  -17.1614
            17  O1a O    34.9700  -21.3463
            18  C1y C    28.9248  -17.8570
            19  O5a O    30.1363  -15.7762
            20  O1a O    37.3813  -19.9436
            21  C1a C    38.5869  -17.8570
            22  C1x C    29.3537  -19.1728
            23  N1y N    27.5453  -17.8570
            24  C1y C    28.2349  -19.9841
            25  C1x C    27.1222  -19.1728
            26  C1a C    26.7280  -16.7383
            27  C1b C    28.2349  -21.3695
            28  C1b C    27.0295  -22.0535
            29  C1a C    25.8239  -21.3579
BOND        28
            1     3   4 1
            2     3   5 1
            3     3   6 1
            4     4   7 1 #Down
            5     4   8 1
            6     5   9 1
            7     6  10 1
            8     6  11 1 #Up
            9     7  12 1
            10    8  13 1
            11    8  14 1 #Down
            12    9  15 1
            13    9  16 1 #Down
            14   10  17 1 #Up
            15   18  12 1 #Down
            16   12  19 2
            17   15  20 1 #Down
            18   16  21 1
            19   18  22 1
            20   18  23 1
            21   22  24 1
            22   23  25 1
            23   23  26 1
            24   24  27 1 #Up
            25   27  28 1
            26   28  29 1
            27   10  15 1
            28   24  25 1

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