KEGG   DRUG: D02353Help
Entry
D02353                      Drug                                   

Name
Cefadroxil (USP);
Cefadroxil monohydrate;
Duricef (TN)
Product
  Generic
CEFADROXIL (A-S Medication Solutions LLC), CEFADROXIL (Aidarex Pharmaceuticals LLC), CEFADROXIL (Aurobindo Pharma Limited), CEFADROXIL (Aurobindo Pharma Limited), CEFADROXIL (H.J. Harkins Company), CEFADROXIL (Lupin Pharmaceuticals), CEFADROXIL (Lupin Pharmaceuticals), CEFADROXIL (NorthStar Rx LLC), CEFADROXIL (NorthStar Rx LLC), CEFADROXIL (Northstar Rx LLC), CEFADROXIL (Northstar Rx LLC), CEFADROXIL (PD-Rx Pharmaceuticals), CEFADROXIL (PD-Rx Pharmaceuticals), CEFADROXIL (Rebel Distributors Corp), CEFADROXIL (Rebel Distributors Corp), CEFADROXIL (STAT RX USA LLC), CEFADROXIL (STAT Rx USA LLC), CEFADROXIL (Sandoz), CEFADROXIL (TEVA Pharmaceuticals USA), CEFADROXIL (Teva Pharmaceuticals USA), CEFADROXIL (Teva Pharmaceuticals USA), CEFADROXIL (West-Ward Pharmaceutical Corp), CEFADROXIL (Physicians Total Care), CEFADROXIL (Ranbaxy Pharmaceuticals)
Formula
C16H17N3O5S. H2O
Exact mass
381.0995
Mol weight
381.4036
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
ATC code: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Metabolism
Transporter: SLC15A1 [HSA:6564], SCL15A2 [HSA:6565]
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB05 Cefadroxil
      D02353  Cefadroxil (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefadroxil
    D02353  Cefadroxil (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefadroxil [ATC:J01DB05]
      D02353  Cefadroxil (USP)
BRITE hierarchy
Other DBs
CAS: 
66592-87-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C1y C    30.2264  -14.8915
            2   N1y N    30.2264  -16.2906
            3   C2y C    31.4381  -16.9900
            4   C2y C    32.6498  -16.2906
            5   C1x C    32.6498  -14.8915
            6   S2x S    31.4381  -14.1919
            7   C1y C    28.8273  -14.8915
            8   C5x C    28.8273  -16.2906
            9   N1b N    27.6157  -14.1919
            10  C5a C    26.4038  -14.8915
            11  O5a O    26.4038  -16.2906
            12  O5x O    27.6157  -16.9900
            13  C1c C    25.1922  -14.1919
            14  C1a C    33.8801  -17.0012
            15  C6a C    31.4381  -18.3890
            16  O6a O    30.2096  -19.0984
            17  O6a O    32.6328  -19.0789
            18  C8y C    23.9610  -14.9031
            19  C8x C    22.7509  -14.2044
            20  C8x C    21.5407  -14.9031
            21  C8y C    21.5407  -16.3005
            22  C8x C    22.7509  -16.9992
            23  C8x C    23.9610  -16.3005
            24  N1a N    25.1922  -12.7883
            25  O1a O    20.3421  -16.9928
            26  O0  O    35.6300  -15.0500
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up
            27   21  25 1

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