KEGG   DRUG: D02376Help
Entry
D02376                      Drug                                   

Name
Cefepime (USAN/INN);
CFPM
Formula
C19H24N6O5S2
Exact mass
480.125
Mol weight
480.5611
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DE Fourth-generation cephalosporins
     J01DE01 Cefepime
      D02376  Cefepime (USAN/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefepime
    D02376  Cefepime (USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefepime
      D02376  Cefepime (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
88040-23-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C1y C    26.1037  -19.5155
            2   N1y N    26.1037  -20.9081
            3   C2y C    27.3098  -21.6043
            4   C2y C    28.5158  -20.9081
            5   C1x C    28.5158  -19.5155
            6   S2x S    27.3098  -18.8192
            7   C1y C    24.7110  -19.5155
            8   C5x C    24.7110  -20.9081
            9   N1b N    23.5053  -18.8192
            10  C5a C    22.2991  -19.5155
            11  O5a O    22.2991  -20.9081
            12  O5x O    23.5053  -21.6043
            13  C2c C    21.0930  -18.8192
            14  C1b C    29.7404  -21.6154
            15  C8y C    19.8677  -19.5271
            16  N2y N    30.9514  -20.9165 #+
            17  C8x C    18.7560  -18.6662
            18  S2x S    17.5894  -19.4566
            19  C8y C    17.9809  -20.8102
            20  N5x N    19.3891  -20.8565
            21  N2b N    21.0929  -17.4052
            22  C6a C    27.3098  -23.0135
            23  O6a O    28.5265  -23.7159 #-
            24  O6a O    26.0948  -23.7151
            25  C1x C    30.9516  -19.5037
            26  C1x C    32.2950  -21.3532
            27  C1x C    33.1255  -20.2103
            28  C1x C    32.2953  -19.0672
            29  C1a C    30.9514  -22.3205
            30  N1a N    17.1521  -21.9174
            31  O2a O    22.2830  -16.7186
            32  C1a C    22.2833  -15.3385
BOND        35
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   14  16 1
            18   15  17 2
            19   17  18 1
            20   18  19 1
            21   19  20 2
            22   15  20 1
            23   13  21 2
            24    3  22 1
            25   22  23 1
            26   22  24 2
            27   16  25 1
            28   16  26 1
            29   26  27 1
            30   27  28 1
            31   25  28 1
            32   16  29 1
            33   19  30 1
            34   21  31 1
            35   31  32 1

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