KEGG   DRUG: D02381Help
Entry
D02381                      Drug                                   

Name
Aspartame (NF/INN)
Formula
C14H18N2O5
Exact mass
294.1216
Mol weight
294.3031
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Sweetener
Remark
Same as: 
Target
taste receptor type 1 member 2 (TAS1R2) agonist [HSA:80834] [KO:K04625];
taste receptor type 1 member 3 (TAS1R3) agonist [HSA:83756] [KO:K04626]
  Pathway
hsa04742  Taste transduction
hsa04973  Carbohydrate digestion and absorption  
 
Brite
Pharmaceutical additives [BR:br08316]
 Sweetening agent
  D02381  [109295] Aspartame
 Flavoring substance
  D02381  [109295] Aspartame; alpha-Aspartyl-L-Phenylalanine methyl ester
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Metabotropic glutamate receptor family
   Chemoreception
    taste receptor type 1
     Aspartame
      D02381  Aspartame (NF/INN)
BRITE hierarchy
Other DBs
CAS: 
22839-47-0
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8y C    21.6348  -15.1239
            2   C8x C    22.8469  -15.8287
            3   C8x C    24.0611  -15.1268
            4   C8x C    24.0628  -13.7269
            5   C8x C    22.8503  -13.0293
            6   C8x C    21.6365  -13.7241
            7   O6a O    13.1555  -17.2454
            8   C6a C    14.3678  -17.9364
            9   C1b C    15.5801  -17.2385
            10  C1c C    16.7925  -17.9293
            11  C5a C    17.9977  -17.2314
            12  N1b N    19.2100  -17.9221
            13  C1c C    20.4224  -17.2243
            14  C7a C    21.6348  -17.9152
            15  O7a O    22.8469  -17.2173
            16  C1a C    24.0594  -17.9547
            17  O6a O    14.3608  -19.3388
            18  N1a N    16.7854  -19.3319
            19  O5a O    17.9906  -15.8287
            20  O6a O    21.6044  -19.3177
            21  C1b C    20.4224  -15.8287
BOND        21
            1    10  11 1
            2     5   6 2
            3    11  12 1
            4     6   1 1
            5    12  13 1
            6    13  14 1
            7     1   2 2
            8    14  15 1
            9     7   8 1
            10   15  16 1
            11    2   3 1
            12    8  17 2
            13    8   9 1
            14   10  18 1 #Up
            15    3   4 2
            16   11  19 2
            17    9  10 1
            18   14  20 2
            19    4   5 1
            20   13  21 1 #Up
            21   21   1 1

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