KEGG   DRUG: PrimidololHelp
Entry
D02389                      Drug                                   

Name
Primidolol (USAN/INN)
Formula
C17H23N3O4
Exact mass
333.1689
Mol weight
333.3822
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
Same as: 
Activity
Anti-anginal, Antiarrhythmic, Antihypertensive, beta-Adrenergic receptor antagonist
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Primidolol
      D02389  Primidolol (USAN/INN)
    beta2-adrenergic receptor
     Primidolol
      D02389  Primidolol (USAN/INN)
    beta3-adrenergic receptor
     Primidolol
      D02389  Primidolol (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
67227-55-8
PubChem: 
ChEBI: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8x C    19.3795  -21.0989
            2   C8x C    19.3736  -19.6906
            3   C8x C    18.1641  -21.8000
            4   C8y C    18.1641  -18.9895
            5   C8x C    16.9489  -21.0929
            6   C8y C    16.9489  -19.6906
            7   C1a C    15.7336  -18.9895
            8   O2a O    18.0954  -17.5916
            9   C1b C    19.3768  -16.8938
            10  C1c C    20.5868  -17.5941
            11  C1b C    21.7981  -16.8964
            12  N1b N    23.0079  -17.5965
            13  C1b C    24.2193  -16.8989
            14  C1b C    25.4293  -17.5990
            15  O1a O    20.5853  -18.9920
            16  N4y N    26.6381  -16.9004
            17  C8x C    27.8504  -17.6016
            18  C8y C    29.0638  -16.9021
            19  C8y C    29.0648  -15.5017
            20  N4x N    27.8525  -14.8005
            21  C8y C    26.6391  -15.5000
            22  C1a C    30.2740  -17.6019
            23  O5x O    25.4289  -14.8002
            24  O5x O    30.2760  -14.8036
BOND        25
            1    11  12 1
            2     4   6 2
            3    12  13 1
            4     6   7 1
            5    13  14 1
            6    14  16 1
            7     5   6 1
            8    15  10 1
            9     4   8 1
            10    1   2 2
            11    8   9 1
            12    1   3 1
            13    9  10 1
            14   16  17 1
            15   17  18 2
            16   18  19 1
            17   19  20 1
            18   20  21 1
            19   21  16 1
            20    2   4 1
            21   18  22 1
            22   10  11 1
            23   21  23 2
            24    3   5 2
            25   19  24 2

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