KEGG   DRUG: Flutropium bromideHelp
Entry
D02417                      Drug                                   

Name
Flutropium bromide (JAN);
Flutropium bromide monohydrate;
Flubron (TN)
Formula
C24H29FNO3. Br. H2O
Exact mass
495.142
Mol weight
496.4096
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Activity
Bronchodilator
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Flutropium
      D02417  Flutropium bromide (JAN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D02417  Flutropium bromide (JAN)
BRITE hierarchy
Other DBs
PubChem: 
LigandBox: 
KCF data Show

ATOM        31
            1   O0  O    34.0872  -14.6179
            2   C1x C    21.0238  -16.4308
            3   C1x C    21.3519  -15.2591
            4   C1y C    22.1955  -16.1496
            5   C1y C    22.5236  -14.9779
            6   N2y N    21.2582  -13.6656 #+
            7   C1x C    24.0702  -16.1496
            8   C1x C    23.7890  -14.9779
            9   C1y C    25.1013  -16.7120
            10  O7a O    26.1793  -17.6025
            11  C7a C    27.3979  -17.6025
            12  C1d C    28.0072  -16.5245
            13  O6a O    28.0072  -18.7273
            14  C8y C    29.2258  -16.5245
            15  C8y C    27.3979  -15.4934
            16  C8x C    29.9320  -17.7482
            17  C8x C    31.3320  -17.7485
            18  C8x C    32.0322  -16.5362
            19  C8x C    31.3261  -15.3125
            20  C8x C    29.9261  -15.3122
            21  C1a C    20.5091  -12.4814
            22  C1b C    20.0289  -14.2783
            23  C1b C    18.8562  -13.5018
            24  X   F    17.5790  -14.1385
            25  C8x C    25.9979  -15.4934
            26  C8x C    28.0979  -14.2810
            27  C8x C    27.3979  -13.0685
            28  C8x C    25.9979  -13.0685
            29  C8x C    25.2979  -14.2810
            30  O1a O    29.2672  -14.3321
            31  X   Br   22.6100  -12.3900 #-
BOND        32
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     4   6 1
            5     4   7 1
            6     5   8 1
            7     7   9 1
            8     9  10 1 #Down
            9    10  11 1
            10   11  12 1
            11   11  13 2
            12   12  14 1
            13   12  15 1
            14    5   6 1
            15    8   9 1
            16   14  16 2
            17   16  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 2
            21   14  20 1
            22    6  21 1
            23    6  22 1
            24   22  23 1
            25   23  24 1
            26   15  25 1
            27   15  26 2
            28   26  27 1
            29   27  28 2
            30   28  29 1
            31   25  29 2
            32   12  30 1

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