| Entry |
|
|---|
| Name |
Fadrozole hydrochloride (USAN) |
|---|
| Formula |
C14H13N3. HCl
|
|---|
| Exact mass |
259.0876
|
|---|
| Mol weight |
259.7341
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01596 Aromatase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Estrogen biosynthesis inhibitor |
|---|
| Comment |
Aromatase inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Structure map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
DG01292 Fadrozole
D02451 Fadrozole hydrochloride
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP19A1 (ARO)
D02451 Fadrozole hydrochloride (USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
DG01292 Fadrozole
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C8y C 16.8400 -13.3714
2 C8x C 16.1410 -12.1599
3 C8x C 14.7430 -12.1599
4 C8y C 14.0440 -13.3714
5 C8x C 14.7430 -14.5831
6 C8x C 16.1410 -14.5831
7 N4y N 18.9370 -12.1599
8 C1y C 18.2380 -13.3714
9 C1x C 18.9370 -14.5831
10 C1x C 20.3350 -14.5831
11 C1x C 21.0340 -13.3714
12 C8y C 20.3350 -12.1599
13 C8x C 20.8010 -10.8085
14 N5x N 19.6360 -10.0163
15 C8x C 18.5176 -10.8085
16 C3b C 12.6461 -13.3714
17 N3a N 11.2481 -13.3714
18 X Cl 22.7582 -13.0918
BOND 19
1 3 4 1
2 4 5 2
3 7 8 1
4 8 9 1
5 9 10 1
6 10 11 1
7 11 12 1
8 12 7 1
9 5 6 1
10 6 1 2
11 12 13 2
12 13 14 1
13 14 15 2
14 15 7 1
15 8 1 1
16 4 16 1
17 1 2 1
18 16 17 3
19 2 3 2
|
|---|
