KEGG   DRUG: Gemifloxacin mesylateHelp
Entry
D02471                      Drug                                   

Name
Gemifloxacin mesylate (USAN);
Factive (TN)
Product
Formula
C18H20FN5O4. CH4SO3
Exact mass
485.138
Mol weight
485.4866
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621] [KO:K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA15 Gemifloxacin
      D02471  Gemifloxacin mesylate (USAN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Gemifloxacin
    D02471  Gemifloxacin mesylate (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Gemifloxacin
      D02471  Gemifloxacin mesylate (USAN)
Antibacterials [br08350.html]
 D02471
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D02471
BRITE hierarchy
Other DBs
CAS: 
210353-53-0
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        33
            1   C8y C    30.2409  -13.5574
            2   C8y C    30.2409  -14.9575
            3   N4y N    31.4533  -15.6575
            4   C8x C    32.6659  -14.9575
            5   C8y C    32.6659  -13.5574
            6   C8y C    31.4533  -12.8573
            7   C8x C    29.0284  -12.8573
            8   C8y C    27.8159  -13.5574
            9   C8y C    27.8159  -14.9575
            10  N5x N    29.0284  -15.6575
            11  C6a C    33.8798  -12.8565
            12  O6a O    35.0935  -13.5574
            13  O6a O    33.8798  -11.4573
            14  O5x O    31.4533  -11.4573
            15  X   F    26.6020  -12.8565
            16  N1y N    26.6020  -15.6583
            17  C1y C    31.4533  -17.0576
            18  C1x C    30.7542  -18.2709
            19  C1x C    32.1543  -18.2709
            20  C1x C    25.2614  -15.2410
            21  C2y C    24.4511  -16.3846
            22  C1y C    25.2884  -17.5087
            23  C1x C    26.6162  -17.0598
            24  C1b C    24.8762  -18.8311
            25  N2b N    23.0275  -16.4015
            26  O2a O    22.3131  -15.1974
            27  C1a C    20.9177  -15.2140
            28  N1a N    23.4762  -18.8311
            29  C1a C    38.7813  -15.1908
            30  S4a S    40.1814  -15.1908
            31  O1d O    40.1814  -16.5908
            32  O1d O    41.5815  -15.1908
            33  O1d O    40.1814  -13.7907
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    2  10 1
            12    5  11 1
            13   11  12 1
            14   11  13 2
            15    6  14 2
            16    8  15 1
            17    9  16 1
            18    3  17 1
            19   17  18 1
            20   17  19 1
            21   19  18 1
            22   16  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   16  23 1
            27   22  24 1
            28   21  25 2
            29   25  26 1
            30   26  27 1
            31   24  28 1
            32   29  30 1
            33   30  31 2
            34   30  32 1
            35   30  33 2

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