KEGG   DRUG: Dihydrostreptomycin sulfateHelp
Entry
D02512                      Drug                                   

Name
Dihydrostreptomycin sulfate (USP)
Formula
(C21H41N7O12)2. 3H2SO4
Exact mass
1460.4648
Mol weight
1461.4153
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Protein biosynthesis inhibitor
Comment
Aminoglycoside
Target
  Pathway
Ribosome
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA15 Dihydrostreptomycin
      D02512  Dihydrostreptomycin sulfate (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   30S subunit inhibitor
    Aminoglycosides
     Dihydrostreptomycin
      D02512  Dihydrostreptomycin sulfate (USP)
BRITE hierarchy
Other DBs
CAS: 
5490-27-7
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        95
            1   O1d O    32.5996  -18.3280
            2   S4a S    33.9812  -18.3280
            3   O1d O    33.9812  -19.7097
            4   O1d O    35.3630  -18.3280
            5   O1d O    33.9812  -16.9463
            6   C1y C    20.2300  -20.8600
            7   C1y C    20.2300  -22.2600
            8   C1y C    21.4900  -22.9600
            9   C1y C    22.6800  -22.2600
            10  O2x O    22.6800  -20.8600
            11  C1y C    21.4900  -20.1600
            12  O2a O    21.4900  -18.8300
            13  N1b N    19.0400  -20.1600
            14  O1a O    21.4900  -24.3600
            15  C1b C    24.1500  -22.9600
            16  O1a O    19.0400  -22.9600
            17  C1y C    23.8700  -16.6600
            18  C1y C    23.8700  -18.0600
            19  C1y C    25.1300  -18.7600
            20  C1y C    26.3200  -18.0600
            21  C1y C    26.3200  -16.6600
            22  C1y C    25.1300  -15.9600
            23  O1a O    27.5100  -15.9600
            24  O2a O    22.4000  -15.9600
            25  O1a O    25.1300  -20.1600
            26  N1b N    25.1300  -14.6300
            27  O1a O    22.7500  -18.7600
            28  N1b N    27.5100  -18.7600
            29  C1y C    20.6500  -17.7100
            30  C1y C    21.0700  -16.3800
            31  O2x O    19.9500  -15.5400
            32  C1y C    18.8300  -16.3800
            33  C1z C    19.2500  -17.7100
            34  C1a C    17.5700  -15.9600
            35  C1b C    18.4800  -18.8300
            36  C2c C    26.3200  -13.9300
            37  N2a N    26.3200  -12.5300
            38  N1a N    27.5100  -14.6300
            39  C1a C    17.9200  -20.8600
            40  O1a O    25.4100  -22.2600
            41  C2c C    27.5100  -20.4400
            42  N1a N    26.3200  -21.1400
            43  N2a N    28.7000  -21.1400
            44  O1a O    17.0800  -18.6900
            45  O1a O    19.2500  -19.1100
            46  O1d O    32.5996  -18.3280
            47  S4a S    33.9812  -18.3280
            48  O1d O    33.9812  -19.7097
            49  O1d O    35.3630  -18.3280
            50  O1d O    33.9812  -16.9463
            51  O1d O    32.5996  -18.3280
            52  S4a S    33.9812  -18.3280
            53  O1d O    33.9812  -19.7097
            54  O1d O    35.3630  -18.3280
            55  O1d O    33.9812  -16.9463
            56  C1y C    20.2300  -20.8600
            57  C1y C    20.2300  -22.2600
            58  C1y C    21.4900  -22.9600
            59  C1y C    22.6800  -22.2600
            60  C1b C    24.1500  -22.9600
            61  O1a O    25.4100  -22.2600
            62  O2x O    22.6800  -20.8600
            63  C1y C    21.4900  -20.1600
            64  O2a O    21.4900  -18.8300
            65  C1y C    20.6500  -17.7100
            66  C1y C    21.0700  -16.3800
            67  O2x O    19.9500  -15.5400
            68  C1y C    18.8300  -16.3800
            69  C1z C    19.2500  -17.7100
            70  C1b C    18.4800  -18.8300
            71  O1a O    17.0800  -18.6900
            72  O1a O    19.2500  -19.1100
            73  C1a C    17.5700  -15.9600
            74  O2a O    22.4000  -15.9600
            75  C1y C    23.8700  -16.6600
            76  C1y C    23.8700  -18.0600
            77  O1a O    22.7500  -18.7600
            78  C1y C    25.1300  -18.7600
            79  C1y C    26.3200  -18.0600
            80  N1b N    27.5100  -18.7600
            81  C2c C    27.5100  -20.4400
            82  N1a N    26.3200  -21.1400
            83  N2a N    28.7000  -21.1400
            84  C1y C    26.3200  -16.6600
            85  C1y C    25.1300  -15.9600
            86  N1b N    25.1300  -14.6300
            87  C2c C    26.3200  -13.9300
            88  N2a N    26.3200  -12.5300
            89  N1a N    27.5100  -14.6300
            90  O1a O    27.5100  -15.9600
            91  O1a O    25.1300  -20.1600
            92  O1a O    21.4900  -24.3600
            93  O1a O    19.0400  -22.9600
            94  N1b N    19.0400  -20.1600
            95  C1a C    17.9200  -20.8600
BOND        96
            1     1   2 1
            2     2   3 2
            3     2   4 1
            4     2   5 2
            5    46  47 1
            6    47  48 2
            7    47  49 1
            8    47  50 2
            9    51  52 1
            10   52  53 2
            11   52  54 1
            12   52  55 2
            13    6   7 1
            14   18  27 1 #Up
            15    9  15 1 #Up
            16   20  28 1 #Up
            17    7   8 1
            18    7  16 1 #Up
            19    8   9 1
            20    9  10 1
            21   10  11 1
            22   29  30 1
            23   30  31 1
            24   31  32 1
            25   32  33 1
            26   33  29 1
            27   29  12 1 #Down
            28   11   6 1
            29   32  34 1 #Down
            30   33  35 1 #Up
            31   30  24 1 #Up
            32   11  12 1 #Down
            33   26  36 1
            34   17  18 1
            35   36  37 2
            36   18  19 1
            37   36  38 1
            38   19  20 1
            39   13  39 1
            40   20  21 1
            41   15  40 1
            42   21  22 1
            43   28  41 1
            44   22  17 1
            45   41  42 1
            46   41  43 2
            47   21  23 1 #Down
            48   35  44 1
            49    6  13 1 #Down
            50   33  45 1
            51   17  24 1 #Down
            52   19  25 1 #Down
            53    8  14 1 #Down
            54   22  26 1 #Up
            55   56  57 1
            56   76  77 1 #Up
            57   59  60 1 #Up
            58   79  80 1 #Up
            59   57  58 1
            60   57  93 1 #Up
            61   58  59 1
            62   59  62 1
            63   62  63 1
            64   65  66 1
            65   66  67 1
            66   67  68 1
            67   68  69 1
            68   69  65 1
            69   65  64 1 #Down
            70   63  56 1
            71   68  73 1 #Down
            72   69  70 1 #Up
            73   66  74 1 #Up
            74   63  64 1 #Down
            75   86  87 1
            76   75  76 1
            77   87  88 2
            78   76  78 1
            79   87  89 1
            80   78  79 1
            81   94  95 1
            82   79  84 1
            83   60  61 1
            84   84  85 1
            85   80  81 1
            86   85  75 1
            87   81  82 1
            88   81  83 2
            89   84  90 1 #Down
            90   70  71 1
            91   56  94 1 #Down
            92   69  72 1
            93   75  74 1 #Down
            94   78  91 1 #Down
            95   58  92 1 #Down
            96   85  86 1 #Up
BRACKET     1    31.1500  -20.5800   31.1500  -16.0300
            1    36.5400  -16.0300   36.5400  -20.5800
            1  3
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   46  47  48  49  50  51  52  53  54  55
            2    15.8200  -24.6400   15.8200  -12.1100
            2    29.8900  -12.1100   29.8900  -24.6400
            2  2
 ORIGINAL  2    6   7   8   9  15  40  10  11  12  29  30  31  32  33  35  44
            2   45  34  24  17  18  27  19  20  28  41  42  43  21  22  26  36
            2   37  38  23  25  14  16  13  39
 REPEAT    2   56  57  58  59  60  61  62  63  64  65  66  67  68  69  70  71
            2   72  73  74  75  76  77  78  79  80  81  82  83  84  85  86  87
            2   88  89  90  91  92  93  94  95

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