| Entry |
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| Name |
Garenoxacin mesilate hydrate (JAN);
Garenoxacin mesylate (USAN)
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| Formula |
C23H20F2N2O4. CH4SO3. H2O
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| Exact mass |
540.1378
|
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| Mol weight |
540.5336
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| Structure |
     |
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| Activity |
Antibacterial agent
|
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| Remark |
Therapeutic category: ATC code: |
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| Target |
|
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| Interaction |
Transporter inhibition: SLCO1B1 [HSA: 10599]
 |
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| Structure map |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6241 Pyridonecarboxylic acids
D02540 Garenoxacin mesilate hydrate (JAN); Garenoxacin mesylate (USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA19 Garenoxacin
D02540 Garenoxacin mesilate hydrate (JAN); Garenoxacin mesylate (USAN)
Antiinfectives [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor [KO:K02469 K02470 K02621 K02622]
Fluoroquinolones
Garenoxacin [ATC:J01MA19]
D02540 Garenoxacin mesilate hydrate (JAN); Garenoxacin mesylate (USAN)
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| Other DBs |
CAS: 223652-90-2 PubChem: LigandBox: |
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| KCF data |
ATOM 37
1 C8y C 25.0251 -15.3102
2 C8x C 25.0251 -13.9059
3 C8x C 26.2188 -13.2037
4 C8y C 27.4826 -13.9059
5 C8y C 27.4826 -15.3102
6 C8y C 26.2188 -16.0123
7 C8y C 28.6763 -13.2037
8 C8y C 29.8700 -13.9059
9 C8x C 29.8700 -15.3102
10 N4y N 28.6763 -16.0123
11 O5x O 28.6763 -11.7994
12 C8y C 23.8314 -16.0123
13 C8x C 23.8314 -17.4166
14 C8x C 22.5676 -18.1188
15 C8y C 21.3739 -17.4166
16 C8y C 21.3739 -16.0123
17 C8x C 22.5676 -15.3102
18 O2a O 26.2188 -18.2566
19 C6a C 31.0636 -13.2037
20 O6a O 32.2573 -13.9059
21 O6a O 31.0636 -11.7994
22 C1x C 20.0398 -15.5910
23 N1x N 19.1972 -16.7145
24 C1y C 20.0398 -17.8379
25 C1a C 19.6185 -19.1720
26 C1y C 28.6763 -17.4166
27 C1x C 27.9742 -18.6103
28 C1x C 29.3785 -18.6103
29 C1c C 25.0244 -18.9467
30 X F 25.0244 -20.3467
31 X F 23.7968 -18.2376
32 C1a C 34.7198 -15.6608
33 S4a S 36.1241 -15.6608
34 O1d O 36.1241 -17.0651
35 O1d O 37.5284 -15.6608
36 O1d O 36.1241 -14.2565
37 O0 O 36.8418 -18.6706
BOND 39
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 5 10 1
12 7 11 2
13 1 12 1
14 12 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 16 17 1
19 12 17 2
20 6 18 1
21 8 19 1
22 19 20 1
23 19 21 2
24 16 22 1
25 22 23 1
26 23 24 1
27 15 24 1
28 24 25 1 #Up
29 10 26 1
30 27 28 1
31 28 26 1
32 26 27 1
33 18 29 1
34 29 30 1
35 29 31 1
36 32 33 1
37 33 34 2
38 33 35 1
39 33 36 2
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