KEGG   DRUG: Lomefloxacin mesylateHelp
Entry
D02541                      Drug                                   

Name
Lomefloxacin mesylate (USAN)
Formula
C17H19F2N3O3. CH4SO3
Exact mass
447.1276
Mol weight
447.4535
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA07 Lomefloxacin
      D02541  Lomefloxacin mesylate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE04 Lomefloxacin
      D02541  Lomefloxacin mesylate (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Lomefloxacin
      D02541  Lomefloxacin mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
114394-67-1
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        30
            1   C8y C    21.4900  -15.7500
            2   C8y C    21.4900  -14.3500
            3   N4y N    22.7500  -16.4500
            4   C8y C    20.3000  -16.4500
            5   C8y C    22.7500  -13.6500
            6   C8x C    20.3000  -13.6500
            7   C8x C    24.0100  -15.7500
            8   C1b C    22.7500  -17.8500
            9   C8y C    19.1100  -15.8200
            10  X   F    20.3000  -17.8500
            11  C8y C    24.0100  -14.3500
            12  O5x O    22.7500  -12.2500
            13  C8y C    19.1100  -14.4200
            14  N1y N    17.8500  -16.5200
            15  C6a C    25.2000  -13.6500
            16  X   F    17.8500  -13.7900
            17  C1x C    17.8500  -17.9200
            18  C1x C    16.6600  -15.8900
            19  O6a O    25.2000  -12.2500
            20  O6a O    26.3900  -14.3500
            21  C1y C    16.6600  -18.6900
            22  C1x C    15.4700  -16.5900
            23  N1x N    15.4700  -17.9900
            24  C1a C    16.6600  -20.0900
            25  C1a C    21.5600  -18.5500
            26  C1a C    30.5200  -16.2400
            27  S4a S    31.9200  -16.2400
            28  O1d O    31.9200  -17.6400
            29  O1d O    33.3200  -16.2400
            30  O1d O    31.9200  -14.8400
BOND        31
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 2
            12    6  13 2
            13    9  14 1
            14   11  15 1
            15   13  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 2
            19   15  20 1
            20   17  21 1
            21   18  22 1
            22   21  23 1
            23   21  24 1
            24    7  11 2
            25    9  13 1
            26   22  23 1
            27    8  25 1
            28   26  27 1
            29   27  28 2
            30   27  29 1
            31   27  30 2

» Japanese version   » Back

DBGET integrated database retrieval system