KEGG   DRUG: D02544Help
Entry
D02544                      Drug                                   

Name
Sisomicin (USAN/INN);
SISO
Formula
C19H37N5O7
Exact mass
447.2693
Mol weight
447.5264
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Micromonospora inyoensis [TAX:47866]
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Natural product
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB08 Sisomicin
      D02544  Sisomicin (USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Aminoglycosides
     Sisomicin
      D02544  Sisomicin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
32385-11-8
PubChem: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C1y C    24.5413  -19.3649
            2   C1y C    25.7993  -20.0638
            3   C1y C    24.5413  -17.9671
            4   O2a O    23.3531  -20.0638
            5   C1x C    26.9875  -19.3649
            6   N1a N    25.7294  -21.4616
            7   C1y C    25.7993  -17.2682
            8   O1a O    23.3531  -17.2682
            9   C1y C    22.1650  -20.7627
            10  C1y C    26.9875  -17.9671
            11  O2a O    25.7993  -15.8703
            12  C1y C    22.1650  -22.1605
            13  O2x O    20.9070  -20.0638
            14  N1a N    28.3154  -17.6176
            15  C1y C    27.0573  -15.1714
            16  C1y C    20.9070  -22.8594
            17  O1a O    23.3531  -22.8594
            18  C1x C    19.7188  -20.7627
            19  O2x O    28.2455  -15.8703
            20  C1y C    27.0573  -13.7736
            21  C1z C    19.7188  -22.1605
            22  N1b N    20.9768  -24.2572
            23  C2y C    29.4336  -15.1714
            24  C1x C    28.2455  -13.0747
            25  N1a N    25.7993  -13.0747
            26  C1a C    19.9285  -25.2357
            27  C2x C    29.4336  -13.7736
            28  C1b C    30.6917  -15.8703
            29  N1a N    30.6917  -17.2682
            30  C1a C    18.5072  -22.8536
            31  O1a O    18.5064  -21.4605
BOND        33
            1    18  21 1
            2    24  27 1
            3     1   2 1
            4     1   3 1
            5     1   4 1 #Down
            6     2   5 1
            7     2   6 1 #Up
            8     3   7 1
            9     3   8 1 #Up
            10    9   4 1 #Down
            11    5  10 1
            12    7  11 1 #Down
            13    9  12 1
            14    9  13 1
            15   10  14 1 #Up
            16   15  11 1 #Down
            17   12  16 1
            18   12  17 1 #Down
            19   13  18 1
            20   15  19 1
            21   15  20 1
            22   16  21 1
            23   16  22 1 #Up
            24   19  23 1
            25   20  24 1
            26   20  25 1 #Down
            27   22  26 1
            28   23  27 2
            29   23  28 1
            30   28  29 1
            31    7  10 1
            32   21  30 1 #Down
            33   21  31 1 #Up

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