KEGG   DRUG: D02560Help
Entry
D02560                      Drug                                   

Name
Brofaromine (INN);
Consonar (TN)
Formula
C14H16BrNO2
Exact mass
309.0364
Mol weight
310.1863
Structure
Mol fileKCF fileDB searchJmolKegDraw
Comment
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Target
monoamine oxidase A (MAO-A) inhibitor [HSA:4128] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Structure map
Antidepressants
Catecholamine transferase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase A (MAO-A)
    Brofaromine
     D02560  Brofaromine (INN)
BRITE hierarchy
Other DBs
CAS: 
63638-91-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8y C    14.2800  -14.7700
            2   C8y C    14.2800  -13.3700
            3   C8y C    13.0676  -12.6700
            4   C8x C    11.8551  -13.3700
            5   C8y C    11.8551  -14.7700
            6   C8x C    13.0676  -15.4700
            7   C8x C    15.6115  -15.2026
            8   C8y C    16.4344  -14.0700
            9   O2x O    15.6115  -12.9374
            10  X   Br   13.0676  -11.2702
            11  O2a O    10.6240  -15.4810
            12  C1a C     9.4188  -14.7853
            13  C1y C    17.8500  -14.0700
            14  C1x C    18.5500  -15.2824
            15  C1x C    19.9500  -15.2824
            16  N1x N    20.6500  -14.0700
            17  C1x C    19.9500  -12.8576
            18  C1x C    18.5500  -12.8576
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    2   9 1
            11    3  10 1
            12    5  11 1
            13   11  12 1
            14    8  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   13  18 1

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