KEGG   DRUG: D02562Help
Entry
D02562                      Drug                                   

Name
Rasagiline mesylate (USAN);
Azilect (TN)
Product
Formula
C12H13N. CH4SO3
Exact mass
267.0929
Mol weight
267.344
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian [DS:H00057]
Remark
ATC code: 
Drug group: 
Target
monoamine oxidase B (MAO-B) inhibitor [HSA:4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Antidepressants
Antiparkinsonian agents
Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04B DOPAMINERGIC AGENTS
    N04BD Monoamine oxidase B inhibitors
     N04BD02 Rasagiline
      D02562  Rasagiline mesylate (USAN)
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Monoamine Oxidase B (MAO-B) Inhibitors
   Rasagiline
    D02562  Rasagiline mesylate (USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase B (MAO-B)
    Rasagiline
     D02562  Rasagiline mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
161735-79-1
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        18
            1   C8y C    19.8358  -20.6271
            2   C8y C    19.8358  -19.2233
            3   C8x C    18.6201  -18.5214
            4   C8x C    17.4042  -19.2233
            5   C8x C    17.4042  -20.6271
            6   C8x C    18.6201  -21.3291
            7   C1y C    21.1709  -21.0609
            8   C1x C    21.9961  -19.9252
            9   C1x C    21.1709  -18.7895
            10  N1b N    21.1694  -22.4521
            11  C1b C    22.3845  -23.1554
            12  C3b C    23.5851  -22.4638
            13  C3a C    24.7493  -21.7502
            14  O1d O    30.5752  -19.7146
            15  S4a S    30.5752  -21.1185
            16  C1a C    29.1714  -21.1185
            17  O1d O    31.9791  -21.1185
            18  O1d O    30.5752  -22.5223
BOND        18
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 1
            10    2   9 1
            11    7  10 1 #Up
            12   10  11 1
            13   11  12 1
            14   12  13 3
            15   14  15 2
            16   15  16 1
            17   15  17 1
            18   15  18 2

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