KEGG   DRUG: D02579Help
Entry
D02579                      Drug                                   

Name
Iproniazid (INN)
Formula
C9H13N3O
Exact mass
179.1059
Mol weight
179.219
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
Same as: 
ATC code: 
Comment
Hydrazide derivatives
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Antidepressants
Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF05 Iproniazide
      D02579  Iproniazid (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO) [HSA:4128 4129] [KO:K00274]
    Iproniazide [ATC:N06AF05]
     D02579  Iproniazid (INN)
BRITE hierarchy
Other DBs
CAS: 
54-92-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        13
            1   C8y C    20.3000  -16.1700
            2   C5a C    21.5600  -16.8700
            3   C8x C    19.1100  -16.8700
            4   C8x C    20.3000  -14.7700
            5   N1b N    22.7500  -16.1700
            6   O5a O    21.5600  -18.2700
            7   C8x C    17.9200  -16.1700
            8   C8x C    19.1100  -14.0700
            9   N1b N    23.9400  -16.8700
            10  N5x N    17.9200  -14.7700
            11  C1c C    25.2000  -16.1700
            12  C1a C    26.3900  -16.8700
            13  C1a C    25.2000  -14.7700
BOND        13
            1     1   4 1
            2     2   5 1
            3     2   6 2
            4     3   7 1
            5     4   8 2
            6     5   9 1
            7     7  10 2
            8     8  10 1
            9     9  11 1
            10    1   2 1
            11   11  12 1
            12    1   3 2
            13   11  13 1

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