KEGG   DRUG: AdalimumabHelp
Entry
D02597                      Drug                                   

Name
Adalimumab (USAN/INN);
Adalimumab (genetical recombination) (JAN);
Humira (TN)
Product
Class
Other
 DG01936  TNF inhibitor
Remark
Therapeutic category: 
ATC code: 
Activity
Anti-inflammatory, Antirheumatic, TNF-alpha inhibitor
Comment
anti-TNF-alpha monoclonal antibody
Treatment of rheumatoid arthritis and other chronic inflammatory disease
Target
TNF (TNFA, TNFSF2) [HSA:7124] [KO:K03156]
  Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
Apoptosis
TGF-beta signaling pathway
Antigen processing and presentation
Natural killer cell mediated cytotoxicity
Rheumatoid arthritis
Interaction
Drug interaction
Structure map
Antirheumatics - DMARDs and biological agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors
     L04AB04 Adalimumab
      D02597  Adalimumab (USAN/INN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immune Suppressants
   Adalimumab
    D02597  Adalimumab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D02597  Adalimumab (USAN/INN); Adalimumab (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   TNF-alpha
    Adalimumab
     D02597  Adalimumab (USAN/INN)
Dermatological agents [br08370.html]
 Non-steroidal injection
  D02597
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02597
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02597
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D02597
BRITE hierarchy
Other DBs
CAS: 
331731-18-1
PubChem: 
DrugBank: 
NIKKAJI: 

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