KEGG   DRUG: D02598Help
Entry
D02598                      Drug                                   

Name
Infliximab (genetical recombination) (JAN);
Infliximab (USAN/INN);
Remicade (TN)
Product
Activity
monoclonal antibody [DS:H00285 H00286 H00287 H00288 H00630]
Remark
Therapeutic category: 
ATC code: 
Comment
anti-TNF-alpha monoclonal antibody
Target
TNF-alpha [HSA:7124] [KO:K03156]
  Pathway
hsa04010  MAPK signaling pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04210  Apoptosis
hsa04350  TGF-beta signaling pathway
hsa04380  Osteoclast differentiation
hsa04612  Antigen processing and presentation
hsa04920  Adipocytokine signaling pathway
hsa05323  Rheumatoid arthritis  
 
Interaction
Drug interaction
Structure map
Antirheumatics - DMARDs and biological agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D02598  Infliximab (genetical recombination) (JAN); Infliximab (USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors
     L04AB02 Infliximab
      D02598  Infliximab (genetical recombination) (JAN); Infliximab (USAN/INN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immune Suppressants
   Tumor Necrosis Factor (TNF) Blockers
    Infliximab
     D02598  Infliximab (genetical recombination) (JAN); Infliximab (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   TNF-alpha [HSA:7124] [KO:K03156]
    Infliximab [ATC:L04AB02]
     D02598  Infliximab (genetical recombination) (JAN); Infliximab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
170277-31-3
PubChem: 
DrugBank: 
NIKKAJI: 

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