KEGG   DRUG: InfliximabHelp
Entry
D02598                      Drug                                   

Name
Infliximab (USAN/INN);
Infliximab (genetical recombination) (JAN);
Infliximab (genetical recombination) [Infliximab biosimilar1] (JAN);
Infliximab (genetical recombination) [Infliximab biosimilar2] (JAN);
Remicade (TN)
Product
Class
Anti-inflammatory
 DG01985  Disease modifying anti-rheumatic drugs (DMARDs)
Other
 DG01936  TNF inhibitor
Remark
Therapeutic category: 
ATC code: 
Activity
Anti-inflammatory, Antirheumatic, Anti-TNF-alpha antibody
  Disease
Crohn's disease [DS:H00286]
Ulcerative colitis [DS:H01466]
Rheumatoid arthritis [DS:H00630]
Ankylosing spondylitis [DS:H01674]
Psoriatic arthritis [DS:H01507]
Plaque psoriasis [DS:H01656]
Target
TNF (TNFA, TNFSF2) [HSA:7124] [KO:K03156]
  Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
Apoptosis
TGF-beta signaling pathway
Osteoclast differentiation
Antigen processing and presentation
Adipocytokine signaling pathway
Rheumatoid arthritis
Interaction
Drug interaction
Structure map
Antirheumatics - DMARDs and biological agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors
     L04AB02 Infliximab
      D02598  Infliximab (USAN/INN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immune Suppressants
   Infliximab
    D02598  Infliximab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D02598  Infliximab (USAN/INN); Infliximab (genetical recombination) (JAN); Infliximab (genetical recombination) [Infliximab biosimilar1] (JAN); Infliximab (genetical recombination) [Infliximab biosimilar2] (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   TNF-alpha
    Infliximab
     D02598  Infliximab (USAN/INN)
Antirheumatic and antigout drugs [br08366.html]
 Antirheumatic drugs
  D02598
Gastrointestinal agents [br08371.html]
 Agents for irritable bowel syndrome, ulcerative colitis
  D02598
Dermatological agents [br08370.html]
 Non-steroidal injection
  D02598
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D02598
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02598
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D02598
BRITE hierarchy
Other DBs
CAS: 
170277-31-3
PubChem: 
DrugBank: 
NIKKAJI: 

» Japanese version   » Back

DBGET integrated database retrieval system