KEGG   DRUG: Orphenadrine hydrochlorideHelp
Entry
D02599                      Drug                                   

Name
Orphenadrine hydrochloride;
Disipal (TN)
Formula
C18H23NO. HCl
Exact mass
305.1546
Mol weight
305.8423
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
 DG01745  Anticholinergic antiparkinson agent
Unclassified
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: 
Chemical group: 
Activity
Antihistaminic, Relaxant [skeletal muscle]
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AB Ethers chemically close to antihistamines
     N04AB02 Orphenadrine (chloride)
      D02599  Orphenadrine hydrochloride
USP drug classification [BR:br08302]
 Skeletal Muscle Relaxants
  Orphenadrine
   D02599  Orphenadrine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Orphenadrine (chloride)
      D02599  Orphenadrine hydrochloride
BRITE hierarchy
Other DBs
CAS: 
341-69-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   X   Cl   41.4554  -19.1198
            2   C1a C    30.9280  -20.7988
            3   N1c N    32.1419  -20.0980
            4   C1b C    33.3557  -20.7988
            5   C1b C    34.5696  -20.0980
            6   O2a O    35.7834  -20.7988
            7   C1c C    36.9972  -20.0980
            8   C8y C    38.2111  -20.7988
            9   C8y C    36.9972  -18.6965
            10  C8x C    38.1983  -18.0030
            11  C8x C    38.1982  -16.6013
            12  C8x C    36.9843  -15.9006
            13  C8x C    35.7833  -16.5941
            14  C8y C    35.7834  -17.9958
            15  C8x C    38.2111  -22.2005
            16  C8x C    39.4250  -22.9013
            17  C8x C    40.6389  -22.2005
            18  C8x C    40.6389  -20.7988
            19  C8x C    39.4250  -20.0980
            20  C1a C    34.5737  -18.6943
            21  C1a C    32.1419  -18.6964
BOND        21
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     7   8 1
            7     7   9 1
            8     9  10 2
            9    10  11 1
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13    9  14 1
            14    8  15 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19    8  19 2
            20   14  20 1
            21    3  21 1

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