KEGG   DRUG: DenopamineHelp
Entry
D02614                      Drug                                   

Name
Denopamine (JAN/INN);
Kalgut (TN)
Formula
C18H23NO4
Exact mass
317.1627
Mol weight
317.3795
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01699  Catecholamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01451  beta1-Adrenergic receptor agonist
 DG01951  Catecholamine adrenergic receptor agonist
Remark
Therapeutic category: 
Activity
Cardiotonic, beta1-Adrenergic receptor agonist
Comment
Dopamine derivative
Target
ADRB1 [HSA:153] [KO:K04141]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D02614  Denopamine (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Denopamine
      D02614  Denopamine (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
71771-90-9
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1a C     8.6800  -17.7800
            2   C1a C     8.6800  -19.1800
            3   O2a O     9.8924  -19.8800
            4   C8y C    11.1049  -19.1800
            5   C8y C    11.1049  -17.7800
            6   O2a O     9.8924  -17.0800
            7   C8x C    12.3173  -19.8800
            8   C8x C    13.5297  -19.1800
            9   C8y C    13.5297  -17.7800
            10  C8x C    12.3173  -17.0800
            11  C1b C    14.7273  -17.0885
            12  C1b C    15.9156  -17.7745
            13  N1b N    17.1064  -17.0869
            14  C1b C    18.2960  -17.7737
            15  C1c C    19.4861  -17.0865
            16  C8y C    20.6762  -17.7735
            17  O1a O    19.4862  -15.6802
            18  C8x C    20.6763  -19.1798
            19  C8x C    21.8888  -19.8796
            20  C8y C    23.1012  -19.1795
            21  C8x C    23.1010  -17.7733
            22  C8x C    21.8885  -17.0734
            23  O1a O    24.3130  -19.8791
BOND        24
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     1   6 1
            6     4   7 2
            7     7   8 1
            8     8   9 2
            9     9  10 1
            10    5  10 2
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   15  17 1 #Down
            18   16  18 2
            19   18  19 1
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   16  22 1
            24   20  23 1

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