KEGG   DRUG: D02622Help
Entry
D02622                      Drug                                   

Name
Pipamperone (USAN/INN);
Floropipamide
Formula
C21H30FN3O2
Exact mass
375.2322
Mol weight
375.4802
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
ATC code: 
Drug group: 
Comment
Butyrophenone derivatives
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157];
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Butyrophenones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AD Butyrophenone derivatives
     N05AD05 Pipamperone
      D02622  Pipamperone (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Pipamperone
      D02622  Pipamperone (USAN/INN)
   Serotonin
    5-HT2A-receptor
     Pipamperone
      D02622  Pipamperone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
1893-33-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C1z C    26.3900  -16.0300
            2   C1x C    25.2000  -15.3300
            3   C1x C    23.9400  -16.0300
            4   N1y N    23.9400  -17.4300
            5   C1x C    25.2000  -18.1300
            6   C1x C    26.3900  -17.4300
            7   C1b C    22.7500  -18.1300
            8   C1b C    21.5600  -17.4300
            9   C1b C    20.3000  -18.1300
            10  C5a C    19.1100  -17.4300
            11  C8y C    17.9200  -18.1300
            12  O5a O    19.1100  -16.0300
            13  C8x C    16.7300  -17.4300
            14  C8x C    15.4700  -18.1300
            15  C8y C    15.4700  -19.5300
            16  C8x C    16.7300  -20.2300
            17  C8x C    17.9200  -19.5300
            18  X   F    14.2800  -20.1600
            19  N1y N    27.5800  -15.3300
            20  C1x C    28.8400  -16.0300
            21  C1x C    30.0300  -15.3300
            22  C1x C    30.0300  -13.9300
            23  C1x C    28.8400  -13.2300
            24  C1x C    27.5800  -13.9300
            25  C5a C    27.0900  -17.2200
            26  N1a N    28.4900  -17.2200
            27  O5a O    26.3900  -18.4100
BOND        29
            1     6   1 1
            2     4   7 1
            3    11  13 2
            4    13  14 1
            5    14  15 2
            6    15  16 1
            7    16  17 2
            8    17  11 1
            9    15  18 1
            10    7   8 1
            11    1  19 1
            12    8   9 1
            13    1   2 1
            14    9  10 1
            15    2   3 1
            16   19  20 1
            17   20  21 1
            18   21  22 1
            19   22  23 1
            20   23  24 1
            21   24  19 1
            22   10  11 1
            23    3   4 1
            24   10  12 2
            25    4   5 1
            26    5   6 1
            27   25  26 1
            28   25   1 1
            29   25  27 2

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