KEGG   DRUG: D02630Help
Entry
D02630                      Drug                                   

Name
Penfluridol (USAN/INN);
Semap (TN)
Formula
C28H27ClF5NO
Exact mass
523.1701
Mol weight
523.9651
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
ATC code: 
Target
calcium channel T type blocker [HSA:8911 8912 8913] [KO:K04856 K04855 K04854]
  Pathway
hsa04010  MAPK signaling pathway
hsa04020  Calcium signaling pathway  
 
Interaction
Drug interaction
Structure map
Butyrophenones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AG Diphenylbutylpiperidine derivatives
     N05AG03 Penfluridol
      D02630  Penfluridol (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Ca2+ channel, CACN alpha-1, CaVx.x
    calcium channel T type
     Penfluridol
      D02630  Penfluridol (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
26864-56-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        36
            1   C8x C     8.6100   -9.9400
            2   C8y C     8.6100  -11.3400
            3   C8x C     9.8224  -12.0400
            4   C8x C    11.0349  -11.3400
            5   C8y C    11.0349   -9.9400
            6   C8x C     9.8224   -9.2400
            7   C8x C    13.4597  -11.3400
            8   C8y C    13.4597   -9.9400
            9   C1c C    12.2473   -9.2400
            10  C8x C    14.6722  -12.0400
            11  C8y C    15.8846  -11.3400
            12  C8x C    15.8846   -9.9400
            13  C8x C    14.6722   -9.2400
            14  X   F     7.3976  -12.0400
            15  X   F    17.1011  -12.0423
            16  C1b C    12.2473   -7.8400
            17  C1b C    13.4618   -7.1388
            18  C1b C    14.6583   -7.8298
            19  N1y N    15.8451   -7.1446
            20  C1x C    17.0366   -7.8328
            21  C1x C    18.2491   -7.1329
            22  C1z C    18.2493   -5.7329
            23  C1x C    17.0578   -5.0448
            24  C1x C    15.8453   -5.7446
            25  C8y C    19.4741   -5.0258
            26  C8x C    20.6820   -5.7232
            27  C8y C    21.8944   -5.0233
            28  C8y C    21.8945   -3.6233
            29  C8x C    20.6867   -2.9259
            30  C8x C    19.4742   -3.6258
            31  X   Cl   23.1112   -2.9209
            32  C1d C    23.1258   -5.7342
            33  X   F    24.3382   -6.4342
            34  X   F    23.8165   -4.5373
            35  X   F    22.4171   -6.9622
            36  O1a O    19.4617   -6.4329
BOND        39
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    2  14 1
            16   11  15 1
            17    9  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   19  24 1
            27   22  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   28  29 1
            32   29  30 2
            33   25  30 1
            34   28  31 1
            35   27  32 1
            36   32  33 1
            37   32  34 1
            38   32  35 1
            39   22  36 1

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