KEGG   DRUG: Talibegron hydrochlorideHelp
Entry
D02702                      Drug                                   

Name
Talibegron hydrochloride (USAN)
Formula
C18H21NO4. HCl
Exact mass
351.1237
Mol weight
351.8246
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01451  beta1-Adrenergic receptor agonist
   DG01452  beta2-Adrenergic receptor agonist
   DG01453  beta3-Adrenergic receptor agonist
Other
 DG01706  Antiobesity
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
Activity
Treatment of obesity in dogs and cats [beta-adrenoreceptor agonist]
Target
beta3-adrenergic receptor [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Talibegron
      D02702  Talibegron hydrochloride (USAN)
    beta2-adrenergic receptor
     Talibegron
      D02702  Talibegron hydrochloride (USAN)
    beta3-adrenergic receptor
     Talibegron
      D02702  Talibegron hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
178600-17-4
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   C8x C    15.1200  -22.4700
            2   C8x C    15.1200  -21.0700
            3   C8x C    16.3100  -20.3700
            4   C8x C    17.5700  -21.0700
            5   C8y C    17.5700  -22.4700
            6   C8x C    16.3100  -23.1700
            7   C1c C    18.7600  -23.1700
            8   C1b C    20.0200  -22.4700
            9   N1b N    21.2100  -23.1700
            10  C1b C    22.4000  -22.4700
            11  C1b C    23.6600  -23.1700
            12  O2a O    24.8500  -22.4700
            13  C8y C    26.0400  -23.1700
            14  O1a O    18.7600  -24.5700
            15  C8x C    27.3000  -22.4700
            16  C8x C    28.4900  -23.1700
            17  C8y C    28.4900  -24.5700
            18  C8x C    27.3000  -25.2700
            19  C8x C    26.0400  -24.5700
            20  C1b C    29.6800  -25.2700
            21  C6a C    30.9400  -24.5700
            22  O6a O    32.1300  -25.2700
            23  O6a O    30.9400  -23.1700
            24  X   Cl   27.3700  -27.3000
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    7  14 1 #Down
            15   13  15 2
            16   15  16 1
            17   16  17 2
            18   17  18 1
            19   18  19 2
            20   13  19 1
            21   17  20 1
            22   20  21 1
            23   21  22 1
            24   21  23 2

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