KEGG   DRUG: LimaprostHelp
Entry
D02722                      Drug                                   

Name
Limaprost (INN)
Formula
C22H36O5
Exact mass
380.2563
Mol weight
380.5182
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01611  Prostaglandin E1 derivative
Other
 DG01961  Prostaglandin derivative
  DG01611  Prostaglandin E1 derivative
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01611  Prostaglandin E1 derivative
Remark
Chemical structure group: DG01271
Product (DG01271): D02860<JP>
Efficacy
Vasodilator, Prostaglandin E1 receptor agonist
Target
PTGER1 [HSA:5731] [KO:K04258]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07035  Prostaglandins
map07228  Eicosanoid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGER1
     D02722  Limaprost (INN)
BRITE hierarchy
Other DBs
CAS: 74397-12-9
PubChem: 17396889
ChEMBL: CHEMBL2107456
LigandBox: D02722
NIKKAJI: J23.220C
KCF data Show

ATOM        27
            1   C1y C    15.8900  -14.8400
            2   C1y C    15.8900  -13.4400
            3   C5x C    14.5585  -13.0074
            4   C1x C    13.7356  -14.1400
            5   C1y C    14.5585  -15.2726
            6   O5x O    14.1297  -11.6878
            7   O1a O    14.1297  -16.5922
            8   C1b C    17.1024  -12.7400
            9   C1b C    18.3149  -13.4400
            10  C1b C    19.5273  -12.7400
            11  C1b C    20.7397  -13.4400
            12  C2b C    21.9522  -12.7400
            13  C2b C    23.1646  -13.4400
            14  C6a C    24.3770  -12.7400
            15  O6a O    25.5895  -13.4400
            16  C2b C    17.1024  -15.5400
            17  C2b C    18.3149  -14.8400
            18  C1c C    19.5273  -15.5400
            19  C1b C    20.7397  -14.8400
            20  C1c C    21.9522  -15.5400
            21  C1b C    23.1646  -14.8400
            22  C1b C    24.3770  -15.5400
            23  C1b C    25.5895  -14.8400
            24  C1a C    26.8019  -15.5400
            25  O6a O    24.3770  -11.3401
            26  O1a O    19.5273  -16.9400
            27  C1a C    21.9522  -16.9397
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     3   6 2
            7     5   7 1 #Down
            8     2   8 1 #Down
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 1
            16    1  16 1 #Up
            17   16  17 2
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   23  24 1
            25   14  25 2
            26   18  26 1 #Down
            27   20  27 1 #Down

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