| Entry |
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| Name |
Abacavir succinate (USAN)
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| Formula |
C14H18N6O. C4H6O4
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| Exact mass |
404.1808
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| Mol weight |
404.4204
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| Structure |
     |
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| Activity |
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| Remark |
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| Comment |
Nucleoside reverse transcriptase inhibitor (NRTI)
Patients who carry the HLA-B*5701 allele are at high risk for experiencing a hypersensitivity reaction to Abacavir
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| Target |
RNA-directed DNA polymerase inhibitor |
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| Interaction |
Genomic biomarker: HLA-B*5701 negative
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
J05AF06 Abacavir
D02734 Abacavir succinate (USAN)
USP drug classification [BR:br08302]
Antivirals
Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
Abacavir
D02734 Abacavir succinate (USAN)
Antiinfectives [BR:br08307]
Antivirals
Anti-HIV agent
Reverse transcriptase inhibitor (RTI)
Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
Abacavir [ATC:J05AF06]
D02734 Abacavir succinate (USAN)
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| Other DBs |
CAS: 168146-84-7 PubChem: LigandBox: |
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| KCF data |
ATOM 29
1 C6a C 30.8546 -17.5451
2 C1b C 32.0651 -16.8462
3 C1b C 33.2755 -17.5451
4 C6a C 34.4860 -16.8462
5 O6a O 35.6965 -17.5451
6 O6a O 30.8546 -18.9428
7 O6a O 34.4860 -15.4485
8 O6a O 29.8663 -16.5568
9 C8y C 23.2400 -16.8700
10 C8y C 23.2400 -18.3400
11 C8y C 24.4300 -16.1700
12 N5x N 22.0500 -16.3800
13 N4y N 21.9800 -18.7600
14 N5x N 24.4300 -19.1100
15 N1b N 24.4300 -14.8400
16 N5x N 25.6900 -16.9400
17 C8x C 21.2100 -17.5000
18 C1y C 20.8600 -19.6700
19 C8y C 25.6900 -18.4100
20 C1y C 25.6900 -14.1400
21 C1x C 19.6700 -18.9000
22 C2x C 20.4400 -21.0000
23 N1a N 26.8800 -19.1800
24 C1x C 27.0900 -14.2100
25 C1x C 26.3900 -12.9500
26 C1y C 18.6200 -19.6700
27 C2x C 19.1100 -21.0000
28 C1b C 17.2900 -19.3200
29 O1a O 16.2400 -20.1600
BOND 31
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 6 2
6 4 7 2
7 1 8 1
8 9 10 2
9 9 11 1
10 9 12 1
11 10 13 1
12 10 14 1
13 11 15 1
14 11 16 2
15 12 17 2
16 18 13 1 #Up
17 14 19 2
18 15 20 1
19 18 21 1
20 18 22 1
21 19 23 1
22 20 24 1
23 20 25 1
24 21 26 1
25 22 27 2
26 26 28 1 #Up
27 28 29 1
28 13 17 1
29 16 19 1
30 24 25 1
31 26 27 1
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