KEGG   DRUG: Interferon alfa-2bHelp
Entry
D02745                      Drug                                   

Name
Interferon alfa-2b (USAN);
Interferon alfa-2b (genetical recombination) (JAN);
Intron A (TN)
Product
Formula
C860H1353N229O255S9
Exact mass
19256.7431
Mol weight
19268.9111
Sequence
CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI
QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR
KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
  Type
Peptide
Class
Antineoplastic
 DG01752  Interferone
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antineoplastic, Antiviral, Biological response modifier
Target
interferon receptor 1 [HSA:3454] [KO:K05130];
interferon receptor 2 [HSA:3455] [KO:K05131]
  Pathway
Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Interaction
Drug interaction
Structure map
Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB05 Interferon alfa-2b
      D02745  Interferon alfa-2b (USAN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Interferon Alfa-2b, Recombinant
    D02745  Interferon alfa-2b (USAN)
  Anti-hepatitis C (HCV) Agents
   Interferon Alfa-2b, Recombinant
    D02745  Interferon alfa-2b (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   639  Miscellaneous
    6399  Others
     D02745  Interferon alfa-2b (USAN); Interferon alfa-2b (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interferon receptor 1
    Interferon alfa-2b
     D02745  Interferon alfa-2b (USAN)
   interferon receptor 2
    Interferon alfa-2b
     D02745  Interferon alfa-2b (USAN)
Antineoplastics [br08340.html]
 D02745
Antivirals [br08351.html]
 D02745
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D02745
BRITE hierarchy
Other DBs
CAS: 
99210-65-8
PubChem: 
DrugBank: 

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