KEGG   DRUG: D02760Help
Entry
D02760                      Drug                                   

Name
Acrivastine (USAN/INN)
Formula
C22H24N2O2
Exact mass
348.1838
Mol weight
348.4382
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihistaminic
Remark
ATC code: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX18 Acrivastine
      D02760  Acrivastine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Acrivastine
      D02760  Acrivastine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
87848-99-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C2b C    18.1776  -14.7000
            2   C8y C    19.3900  -16.8000
            3   C8x C    19.3900  -18.2000
            4   C8x C    20.5800  -18.9000
            5   C8x C    21.8400  -18.2000
            6   C8y C    21.8400  -16.8000
            7   N5x N    20.5800  -16.1000
            8   C2b C    23.0300  -16.1000
            9   C2b C    24.2200  -16.8000
            10  C6a C    25.4800  -16.1000
            11  O6a O    26.6700  -16.8000
            12  O6a O    25.4800  -14.7000
            13  C2c C    18.1776  -16.1000
            14  C8y C    16.9651  -16.8000
            15  C8x C    16.9651  -18.2000
            16  C8x C    15.7527  -16.1000
            17  C8x C    14.5403  -16.8000
            18  C8y C    14.5403  -18.2000
            19  C8x C    15.7527  -18.9000
            20  C1a C    13.3278  -18.9000
            21  C1b C    16.9651  -14.0000
            22  N1y N    16.9651  -12.6000
            23  C1x C    18.1070  -11.7879
            24  C1x C    17.6898  -10.4515
            25  C1x C    16.2898  -10.4353
            26  C1x C    15.8419  -11.7618
BOND        28
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     8   9 2
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12    2  13 1
            13   13  14 1
            14   14  15 1
            15   14  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19   19  15 2
            20   18  20 1
            21    1  13 2
            22    1  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   22  26 1

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