KEGG   DRUG: D02768Help
Entry
D02768                      Drug                                   

Name
Adefovir (USAN/INN)
Formula
C8H12N5O4P
Exact mass
273.0627
Mol weight
273.1857
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00412]
Remark
Same as: 
Drug group: 
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
Target
RNA-directed DNA polymerase inhibitor
Metabolism
Transporter: SLC22A6 [HSA:9356], ABCC4 [HSA:10257]
Interaction
Drug interaction
Brite
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Adefovir
    D02768  Adefovir (USAN/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HBV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Adefovir
      D02768  Adefovir (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
106941-25-7
PubChem: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8y C    30.5268  -18.7216
            2   C8y C    30.5268  -17.2550
            3   N4y N    29.1998  -19.1407
            4   N5x N    31.7839  -19.3502
            5   N5x N    29.1998  -16.8359
            6   C8y C    31.7839  -16.6263
            7   C8x C    28.3617  -18.0232
            8   C8x C    32.9713  -18.7216
            9   N5x N    32.9713  -17.2550
            10  N1a N    31.7839  -15.2295
            11  C1b C    29.1998  -20.5407
            12  C1b C    27.9935  -21.2370
            13  O2a O    26.7745  -20.5331
            14  C1b C    25.5469  -21.2424
            15  P1b P    24.3227  -20.5365
            16  O1c O    23.1102  -19.8365
            17  O1c O    23.6264  -21.7427
            18  O1c O    25.0255  -19.3188
BOND        19
            1     2   5 1
            2     2   6 1
            3     3   7 1
            4     4   8 2
            5     6   9 2
            6     5   7 2
            7     8   9 1
            8     1   2 2
            9     1   3 1
            10    1   4 1
            11    6  10 1
            12    3  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   15  17 1
            19   15  18 2

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