KEGG   DRUG: D02775Help
Entry
D02775                      Drug                                   
Name
Adrogolide hydrochloride (USAN)
Formula
C22H25NO4S. HCl
Exact mass
435.1271
Mol weight
435.9641
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of the symptoms of Parkinson's disease [dopamine D1 receptor agonist]
Target
dopamine D1-receptor agonist [HSA:1812] [KO:K04144]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor [HSA:1812] [KO:K04144]
     Adrogolide
      D02775  Adrogolide hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
166591-11-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   O7a O     8.1200  -13.3700
            2   C7a C     6.8600  -14.0700
            3   C1a C     6.8600  -15.4700
            4   C1x C     5.6700   -9.1700
            5   C1x C     5.6700   -7.7700
            6   C1y C     6.8600   -7.0700
            7   C1y C     8.1200   -7.7700
            8   C8y C     8.1200   -9.1700
            9   C8y C     6.8600   -9.8700
            10  N1x N     6.8600   -5.6700
            11  C1x C     8.1200   -4.9700
            12  C8y C     9.3100   -5.6700
            13  C8y C     9.3100   -7.0700
            14  C8x C     9.3100   -9.8700
            15  C8y C     9.3100  -11.2700
            16  C8y C     8.1200  -11.9700
            17  C8x C     6.8600  -11.2700
            18  O6a O    11.7600   -9.8700
            19  C7a C    11.7600  -11.2700
            20  O7a O    10.5000  -11.9700
            21  S2x S    10.6400   -5.2500
            22  C8y C    11.4800   -6.3700
            23  C8x C    10.6400   -7.4900
            24  C1a C    12.9500  -11.9700
            25  O6a O     5.6700  -13.3700
            26  C1b C    12.6700   -5.6700
            27  C1b C    13.9300   -6.3700
            28  C1a C    15.1200   -5.6700
            29  X   Cl   18.1300  -11.0600
BOND        31
            1     1   2 1
            2     2   3 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8     4   9 1
            9     6  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 2
            13    7  13 1
            14    8  14 2
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17   9 2
            19   18  19 2
            20   19  20 1
            21   15  20 1
            22   12  21 1
            23   21  22 1
            24   22  23 2
            25   13  23 1
            26   19  24 1
            27    1  16 1
            28   25   2 2
            29   22  26 1
            30   26  27 1
            31   27  28 1

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