KEGG   DRUG: D02834Help
Entry
D02834                      Drug                                   

Name
Alprenoxime hydrochloride (USAN)
Formula
C15H22N2O2. HCl
Exact mass
298.1448
Mol weight
298.8083
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiglaucoma agent
Remark
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Alprenoxime
      D02834  Alprenoxime hydrochloride (USAN)
    beta2-adrenergic receptor
     Alprenoxime
      D02834  Alprenoxime hydrochloride (USAN)
    beta3-adrenergic receptor
     Alprenoxime
      D02834  Alprenoxime hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
121009-30-1
PubChem: 
LigandBox: 
KCF data Show

ATOM        20
            1   C8x C    14.9100  -14.8400
            2   C8x C    13.6976  -15.5400
            3   C8x C    13.6976  -16.9400
            4   C8x C    14.9100  -17.6400
            5   C8y C    16.1224  -16.9400
            6   C8y C    16.1224  -15.5400
            7   C1b C    17.3349  -17.6400
            8   C2b C    18.5473  -16.9400
            9   C1b C    18.5473  -15.5400
            10  O2a O    17.3349  -14.8400
            11  C2a C    19.7597  -17.6400
            12  C1b C    20.9722  -15.5400
            13  C2c C    19.7597  -14.8400
            14  N1b N    22.1846  -14.8400
            15  O1b O    20.9721  -12.7400
            16  N2b N    19.7597  -13.4400
            17  C1a C    23.3971  -16.9399
            18  C1c C    23.3971  -15.5399
            19  C1a C    24.6095  -14.8399
            20  X   Cl   28.4900  -16.0300
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     9  10 1
            10    6  10 1
            11    8  11 2
            12   12  13 1
            13    9  13 1
            14   12  14 1
            15   15  16 1
            16   13  16 2
            17   17  18 1
            18   14  18 1
            19   18  19 1

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