KEGG   DRUG: D02860Help
Entry
D02860                      Drug                                   

Name
Limaprost alfadex (JP16);
Opalmon (TN)
Formula
(C36H60O30)x. C22H36O5
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
Drug group: 
Target
prostaglandin E1 receptor agonist [HSA:5731] [KO:K04258]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Prostaglandins
Eicosanoid receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  33  Blood and body fluid agents
   339  Miscellaneous
    3399  Others
     D02860  Limaprost alfadex (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    prostaglandin E1 receptor
     Limaprost
      D02860  Limaprost alfadex (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02860  Limaprost alfadex
BRITE hierarchy
Other DBs
CAS: 
88852-12-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        93
            1   C1y C     7.8056  -15.5840
            2   C1y C     7.8056  -14.1803
            3   C5x C     6.4721  -13.7592
            4   C1x C     5.6299  -14.8821
            5   C1y C     6.4721  -16.0051
            6   O5x O     6.0510  -12.4258
            7   O1a O     6.0510  -17.3385
            8   C1b C     8.9987  -13.4785
            9   C1b C    10.2620  -14.1803
            10  C1b C    11.4551  -13.4785
            11  C1b C    12.6482  -14.1803
            12  C2b C    13.9114  -13.4785
            13  C2b C    15.1045  -14.1803
            14  C6a C    16.2976  -13.4785
            15  O6a O    17.5609  -14.1803
            16  C2b C     8.9987  -16.2858
            17  C2b C    10.2620  -15.5840
            18  C1c C    11.4551  -16.2858
            19  C1b C    12.6482  -15.5840
            20  C1c C    13.9114  -16.2858
            21  C1b C    15.1045  -15.5840
            22  C1b C    16.2976  -16.2858
            23  C1b C    17.5609  -15.5840
            24  C1a C    18.7540  -16.2858
            25  O6a O    16.2976  -12.0748
            26  O1a O    11.4551  -17.6894
            27  C1a C    13.9114  -17.6894
            28  C1y C    35.0700  -11.9700
            29  C1y C    33.7400  -11.9700
            30  O2x O    33.0400  -13.1600
            31  C1y C    33.7400  -14.2800
            32  C1y C    35.0700  -14.2800
            33  C1y C    35.7700  -13.0900
            34  O2x O    33.7400  -17.0100
            35  C1y C    35.0700  -17.0100
            36  O2a O    35.7700  -15.6100
            37  C1y C    33.0400  -18.2000
            38  C1y C    33.7400  -19.3900
            39  C1y C    35.0700  -19.3900
            40  C1y C    35.7700  -18.2000
            41  O1a O    37.1000  -13.0900
            42  O1a O    35.7700  -20.5800
            43  O1a O    35.7700  -10.7800
            44  O1a O    37.1000  -18.2000
            45  O2a O    33.0400  -10.7800
            46  C1y C    31.2200  -10.7800
            47  C1y C    30.4500  -11.9700
            48  O2x O    30.5200  -19.3900
            49  C1y C    31.2200  -20.5800
            50  O2a O    33.1100  -20.5800
            51  C1y C    30.4500   -9.5900
            52  C1y C    29.1200   -9.5900
            53  C1y C    28.4200  -10.7800
            54  O2x O    29.1200  -11.9700
            55  C1y C    29.1900  -19.3900
            56  C1y C    28.4900  -20.5800
            57  C1y C    29.1900  -21.7700
            58  C1y C    30.5200  -21.7700
            59  O1a O    31.2200  -22.9600
            60  O1a O    28.4200   -8.4000
            61  O1a O    31.1500   -8.4000
            62  O2a O    26.6000  -10.7800
            63  O1a O    28.4900  -22.9600
            64  O2a O    26.6700  -20.5800
            65  O2x O    26.6700  -18.2700
            66  C1y C    26.0400  -19.4600
            67  C1y C    26.0400  -11.9700
            68  C1y C    26.6700  -13.1600
            69  C1y C    24.6400  -11.9700
            70  C1y C    24.0100  -13.1600
            71  C1y C    24.6400  -14.3500
            72  O2x O    26.0400  -14.3500
            73  C1y C    26.0400  -17.0800
            74  C1y C    24.6400  -17.0800
            75  C1y C    24.0100  -18.2700
            76  C1y C    24.6400  -19.4600
            77  O1a O    24.0100  -10.7800
            78  O2a O    23.9400  -15.7500
            79  O1a O    22.6100  -18.2700
            80  O1a O    22.6100  -13.1600
            81  O1a O    24.0100  -20.6500
            82  C1b C    28.4200  -18.2000
            83  C1b C    26.7400  -15.8900
            84  C1b C    28.0000  -13.1600
            85  C1b C    31.1500  -13.1600
            86  C1b C    33.0400  -15.5400
            87  C1b C    31.6400  -18.2000
            88  O1a O    29.1900  -17.1500
            89  O1a O    28.1400  -15.8900
            90  O1a O    28.7000  -14.3500
            91  O1a O    30.8000  -14.5600
            92  O1a O    31.7100  -15.6100
            93  O1a O    30.9400  -16.9400
BOND        99
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     3   6 2
            7     5   7 1 #Down
            8     2   8 1 #Down
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 1
            16    1  16 1 #Up
            17   16  17 2
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   23  24 1
            25   14  25 2
            26   18  26 1 #Down
            27   20  27 1 #Down
            28   28  29 1
            29   29  30 1
            30   30  31 1
            31   31  32 1
            32   32  33 1
            33   28  33 1
            34   34  35 1
            35   35  36 1 #Down
            36   32  36 1 #Down
            37   34  37 1
            38   37  38 1
            39   38  39 1
            40   39  40 1
            41   35  40 1
            42   33  41 1 #Up
            43   39  42 1 #Up
            44   28  43 1 #Down
            45   40  44 1 #Down
            46   29  45 1 #Down
            47   46  45 1 #Down
            48   46  47 1
            49   49  48 1
            50   49  50 1 #Down
            51   38  50 1 #Down
            52   46  51 1
            53   51  52 1
            54   52  53 1
            55   53  54 1
            56   47  54 1
            57   48  55 1
            58   55  56 1
            59   56  57 1
            60   57  58 1
            61   49  58 1
            62   58  59 1 #Down
            63   52  60 1 #Down
            64   51  61 1 #Up
            65   53  62 1 #Down
            66   57  63 1 #Up
            67   56  64 1 #Down
            68   65  66 1
            69   66  64 1 #Down
            70   67  62 1 #Down
            71   67  68 1
            72   67  69 1
            73   69  70 1
            74   70  71 1
            75   71  72 1
            76   68  72 1
            77   65  73 1
            78   73  74 1
            79   74  75 1
            80   75  76 1
            81   66  76 1
            82   69  77 1 #Up
            83   71  78 1 #Down
            84   74  78 1 #Down
            85   75  79 1 #Up
            86   70  80 1 #Down
            87   76  81 1 #Down
            88   55  82 1 #Up
            89   73  83 1 #Up
            90   68  84 1 #Up
            91   47  85 1 #Up
            92   31  86 1 #Up
            93   37  87 1 #Up
            94   82  88 1
            95   83  89 1
            96   84  90 1
            97   85  91 1
            98   86  92 1
            99   87  93 1
BRACKET     1    21.0000  -22.5400   21.0000   -7.4200
            1    38.0800   -7.4200   38.0800  -22.5400
            1  x
 ORIGINAL  1   28  29  30  31  32  33  34  35  36  37  38  39  40  41  42  43
            1   44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59
            1   60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75
            1   76  77  78  79  80  81  82  83  84  85  86  87  88  89  90  91
            1   92  93
 REPEAT    1

» Japanese version   » Back

DBGET integrated database retrieval system