KEGG   DRUG: D02923Help
Entry
D02923                      Drug                                   

Name
Amorolfine (USAN/INN);
Loceryl (TN)
Formula
C21H35NO
Exact mass
317.2719
Mol weight
317.5087
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antifungal
Remark
ATC code: 
Drug group: 
Target
squalene epoxidase inhibitor [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis  
 
Structure map
Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE16 Amorolfine
      D02923  Amorolfine (USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Amorolfine
    D02923  Amorolfine (USAN/INN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Amorolfine
    D02923  Amorolfine (USAN/INN)
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   squalene epoxidase inhibitor
    Morpholines
     Amorolfine
      D02923  Amorolfine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
78613-35-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C    17.8290  -17.2793
            2   C8x C    17.8290  -18.6727
            3   C8x C    19.0830  -19.3695
            4   C8y C    20.2674  -18.6727
            5   C8x C    20.2674  -17.2793
            6   C8x C    19.0830  -16.5827
            7   C1b C    21.4518  -19.3695
            8   C1c C    22.6360  -18.6727
            9   C1b C    23.8901  -19.3695
            10  N1y N    25.0744  -18.6727
            11  C1x C    26.2588  -19.3695
            12  C1y C    27.5131  -18.6727
            13  C1a C    22.6360  -17.2793
            14  C1x C    25.0744  -17.2793
            15  C1y C    26.2588  -16.5827
            16  O2x O    27.5129  -17.2793
            17  C1d C    16.6446  -16.5827
            18  C1b C    16.6446  -15.1893
            19  C1a C    15.3906  -17.2793
            20  C1a C    17.6199  -15.6073
            21  C1a C    15.3906  -14.4926
            22  C1a C    26.2411  -15.1647
            23  C1a C    28.7168  -19.4018
BOND        24
            1     4   5 1
            2    11  12 1
            3     5   6 2
            4     6   1 1
            5     8  13 1
            6    10  14 1
            7     4   7 1
            8    14  15 1
            9    12  16 1
            10    7   8 1
            11   15  16 1
            12    1   2 2
            13    1  17 1
            14    8   9 1
            15   17  18 1
            16    2   3 1
            17   17  19 1
            18    9  10 1
            19   17  20 1
            20    3   4 2
            21   18  21 1
            22   10  11 1
            23   15  22 1 #Down
            24   12  23 1 #Down

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