KEGG   DRUG: D02933Help
Entry
D02933                      Drug                                   

Name
Anagrelide hydrochloride (USAN);
Agrylin (TN)
Product
  Generic
Formula
C10H7Cl2N3O. HCl
Exact mass
290.9733
Mol weight
292.549
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antithrombotic
Remark
ATC code: 
Drug group: 
Target
phosphodiesterase (PDE) III inhibitor [HSA:5139 5140] [KO:K13296]
  Pathway
hsa00230  Purine metabolism  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX35 Anagrelide
      D02933  Anagrelide hydrochloride (USAN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Blood Formation Modifiers
   Anagrelide
    D02933  Anagrelide hydrochloride (USAN)
Antineoplastics [BR:br08308]
 Miscellaneous agents
  Platelet-reducing agent
   Anagrelide
    D02933  Anagrelide hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
58579-51-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   N1y N     9.8700   -6.3000
            2   C2y C     9.8700   -7.7000
            3   N2x N     8.6800   -8.4000
            4   C8y C     7.4200   -7.7000
            5   C8y C     7.4200   -6.3000
            6   C1x C     8.6100   -5.6000
            7   C8y C     6.2076   -5.6000
            8   C8y C     4.9951   -6.3000
            9   C8x C     4.9951   -7.7000
            10  C8x C     6.2076   -8.4000
            11  X   Cl    6.2076   -4.2000
            12  X   Cl    3.7827   -5.6000
            13  N1x N    11.2015   -8.1326
            14  C5x C    12.0244   -7.0000
            15  C1x C    11.2015   -5.8674
            16  O5x O    13.4244   -7.0000
            17  X   Cl   16.7300   -7.9800
BOND        18
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   1 1
            6     1   2 1
            7     5   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10   4 1
            12    7  11 1
            13    8  12 1
            14    2  13 1
            15   13  14 1
            16   14  15 1
            17    1  15 1
            18   14  16 2

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