KEGG   DRUG: D02939Help
Entry
D02939                      Drug                                   

Name
Angiotensin amide (USAN);
Angiotensinamide (INN)
Formula
C49H70N14O11
Exact mass
1030.5348
Mol weight
1031.1673
Structure
Mol fileKCF fileDB searchJmolKegDraw
Sequence
NRVYVHPF-NH2
  Type
Peptide
Activity
Vasoconstrictor
Remark
ATC code: 
Comment
Angiotensin analogue
Target
angiotensin II receptor type 1 agonist [HSA:185] [KO:K04166];
angiotensin II receptor type 2 agonist [HSA:186] [KO:K04167]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04614  Renin-angiotensin system  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CX Other cardiac stimulants
     C01CX06 Angiotensinamide
      D02939  Angiotensin amide (USAN); Angiotensinamide (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Angiotensin
    angiotensin II stimulates angiotensin subtype 1 (AT1) receptor
     Angiotensinamide
      D02939  Angiotensin amide (USAN); Angiotensinamide (INN)
    angiotensin II stimulates angiotensin sybtype 2 (AT2) receptor
     Angiotensinamide
      D02939  Angiotensin amide (USAN); Angiotensinamide (INN)
BRITE hierarchy
Other DBs
CAS: 
53-73-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        74
            1   C1y C    37.8890  -24.1549
            2   N1y N    36.5455  -24.1549
            3   C1x C    36.1305  -25.4326
            4   C1x C    37.2173  -26.2223
            5   C1x C    38.3043  -25.4326
            6   C5a C    39.0525  -23.4832
            7   N1b N    40.2160  -24.1549
            8   C1c C    41.3794  -23.4832
            9   C1b C    42.5429  -24.1549
            10  O5a O    39.0525  -22.1398
            11  C6a C    41.3794  -22.1398
            12  O6a O    42.5449  -21.4669
            13  O6a O    40.2179  -21.4692
            14  C8y C    43.7089  -23.4817
            15  C8x C    44.8743  -24.1546
            16  C8x C    46.0378  -23.4829
            17  C8x C    46.0378  -22.1394
            18  C8x C    44.8724  -21.4665
            19  C8x C    43.7089  -22.1383
            20  C5a C    35.3821  -23.4832
            21  C1c C    34.2187  -24.1549
            22  N1b N    33.0553  -23.4832
            23  C5a C    31.8918  -24.1549
            24  C1c C    30.7283  -23.4832
            25  N1b N    29.5650  -24.1549
            26  C5a C    28.4014  -23.4832
            27  O5a O    35.3821  -22.1398
            28  C1b C    34.2187  -27.5580
            29  C8y C    35.3857  -28.2317
            30  C8x C    35.5264  -29.5702
            31  N5x N    36.8427  -29.8501
            32  C8x C    37.5157  -28.6846
            33  N4x N    36.6151  -27.6845
            34  O5a O    31.8918  -25.5018
            35  C1c C    30.7283  -21.4590
            36  C1a C    31.8934  -20.7863
            37  C1a C    29.5658  -20.7878
            38  C1c C    27.2056  -24.1738
            39  O5a O    28.4013  -22.1254
            40  N1b N    26.0205  -23.4898
            41  C5a C    24.8416  -24.1683
            42  C1c C    23.6621  -23.4873
            43  N1b N    22.4826  -24.1683
            44  C5a C    21.3031  -23.4873
            45  C1c C    20.1235  -24.1683
            46  N1b N    18.9440  -23.4873
            47  C5a C    17.7645  -24.1683
            48  O5a O    24.8407  -25.5302
            49  C1c C    23.6621  -21.5786
            50  C1a C    22.4813  -20.8968
            51  C1a C    24.8403  -20.8984
            52  O5a O    21.3031  -22.1253
            53  C1c C    16.5829  -23.4861
            54  O5a O    17.7645  -25.5334
            55  C1b C    15.3992  -24.1696
            56  N1a N    16.5829  -22.1275
            57  C5a C    14.2200  -23.4888
            58  N1a N    13.0386  -24.1709
            59  O5a O    14.2201  -22.1275
            60  C1b C    20.1236  -25.5334
            61  C1b C    21.3022  -26.2138
            62  C1b C    21.3020  -27.5781
            63  N1b N    22.4810  -28.2607
            64  C2c C    22.4794  -29.6231
            65  N1a N    23.6585  -30.3057
            66  N2a N    21.3030  -30.3004
            67  C1b C    27.2057  -25.8760
            68  C8y C    28.3871  -26.5579
            69  C8x C    28.3872  -27.9197
            70  C8x C    29.5671  -28.6008
            71  C8y C    30.7470  -27.9195
            72  C8x C    30.7468  -26.5577
            73  C8x C    29.5668  -25.8766
            74  O1a O    31.9442  -28.6108
BOND        77
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     1   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    6  10 2
            11    8  11 1
            12   11  12 1
            13   11  13 2
            14    9  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   17  18 1
            19   18  19 2
            20   14  19 1
            21    2  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   20  27 2
            29   21  28 1
            30   28  29 1
            31   29  30 2
            32   30  31 1
            33   31  32 2
            34   32  33 1
            35   29  33 1
            36   23  34 2
            37   24  35 1
            38   35  36 1
            39   35  37 1
            40   26  38 1
            41   26  39 2
            42   38  40 1
            43   40  41 1
            44   41  42 1
            45   42  43 1
            46   43  44 1
            47   45  44 1
            48   45  46 1
            49   46  47 1
            50   41  48 2
            51   42  49 1
            52   49  50 1
            53   49  51 1
            54   44  52 2
            55   47  53 1
            56   47  54 2
            57   53  55 1
            58   53  56 1
            59   55  57 1
            60   57  58 1
            61   57  59 2
            62   45  60 1
            63   60  61 1
            64   61  62 1
            65   62  63 1
            66   63  64 1
            67   64  65 1
            68   64  66 2
            69   38  67 1
            70   67  68 1
            71   68  69 2
            72   69  70 1
            73   70  71 2
            74   71  72 1
            75   72  73 2
            76   68  73 1
            77   71  74 1

» Japanese version   » Back

DBGET integrated database retrieval system