KEGG   DRUG: D02973Help
Entry
D02973                      Drug                                   

Name
Aptiganel hydrochloride (USAN)
Formula
C20H21N3. HCl
Exact mass
339.1502
Mol weight
339.8618
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Stroke and traumatic brain injury treatment [NMDA ion channel bloker]
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Aptiganel
      D02973  Aptiganel hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
137160-11-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   C8y C    12.2500  -18.2700
            2   C8y C    12.2500  -19.6700
            3   C8x C    13.4624  -20.3700
            4   C8x C    14.6749  -19.6700
            5   C8y C    14.6749  -18.2700
            6   C8x C    13.4624  -17.5700
            7   C8x C    11.0376  -17.5700
            8   C8x C     9.8251  -18.2700
            9   C8x C     9.8251  -19.6700
            10  C8x C    11.0376  -20.3700
            11  N2a N    17.0997  -19.6700
            12  C2c C    17.0997  -18.2700
            13  N1b N    15.8873  -17.5700
            14  C8x C    19.5246  -19.6700
            15  C8y C    19.5246  -18.2700
            16  N1c N    18.3122  -17.5700
            17  C8x C    20.7370  -20.3700
            18  C8x C    21.9495  -19.6700
            19  C8y C    21.9495  -18.2700
            20  C8x C    20.7370  -17.5700
            21  C1a C    24.3744  -18.2700
            22  C1b C    23.1619  -17.5700
            23  C1a C    18.3122  -16.1703
            24  X   Cl   28.9800  -19.7400
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10   2 1
            12   11  12 2
            13   12  13 1
            14    5  13 1
            15   14  15 1
            16   15  16 1
            17   12  16 1
            18   14  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   15  20 2
            23   21  22 1
            24   19  22 1
            25   16  23 1

» Japanese version   » Back

DBGET integrated database retrieval system