KEGG   DRUG: Aptiganel hydrochlorideHelp
Entry
D02973                      Drug                                   

Name
Aptiganel hydrochloride (USAN)
Formula
C20H21N3. HCl
Exact mass
339.1502
Mol weight
339.8618
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Activity
Stroke treatment, NMDA receptor antagonist
Comment
Stroke and traumatic brain injury treatment
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Long-term potentiation
Glutamatergic synapse
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Aptiganel
      D02973  Aptiganel hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
137160-11-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   C8y C    12.2500  -18.2700
            2   C8y C    12.2500  -19.6700
            3   C8x C    13.4624  -20.3700
            4   C8x C    14.6749  -19.6700
            5   C8y C    14.6749  -18.2700
            6   C8x C    13.4624  -17.5700
            7   C8x C    11.0376  -17.5700
            8   C8x C     9.8251  -18.2700
            9   C8x C     9.8251  -19.6700
            10  C8x C    11.0376  -20.3700
            11  N2a N    17.0997  -19.6700
            12  C2c C    17.0997  -18.2700
            13  N1b N    15.8873  -17.5700
            14  C8x C    19.5246  -19.6700
            15  C8y C    19.5246  -18.2700
            16  N1c N    18.3122  -17.5700
            17  C8x C    20.7370  -20.3700
            18  C8x C    21.9495  -19.6700
            19  C8y C    21.9495  -18.2700
            20  C8x C    20.7370  -17.5700
            21  C1a C    24.3744  -18.2700
            22  C1b C    23.1619  -17.5700
            23  C1a C    18.3122  -16.1703
            24  X   Cl   28.9800  -19.7400
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10   2 1
            12   11  12 2
            13   12  13 1
            14    5  13 1
            15   14  15 1
            16   15  16 1
            17   12  16 1
            18   14  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   15  20 2
            23   21  22 1
            24   19  22 1
            25   16  23 1

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